Best Over The Counter Skin Numbing Cream

Peter | 28-12-2025

You will find our hand-picked selection of Best Over The Counter Skin Numbing Cream below. You have a wide variety of choices of brands such as WELMATE,Nupharmco,tuiwaro,Dr Care,Ebanel available to you as a result of the fact that each one of them has a unique pricing, look, and feel. Continue reading for an in-depth analysis in our Best Over The Counter Skin Numbing Cream buying guide!

Our experts tested a variety of Best Over The Counter Skin Numbing Cream on the market. Right at the top of the list is WELMATE Best Over The Counter Skin Numbing Cream. Check out some more of our favorites below, and read some valuable insight from our experienced editors.

Editor's Choice
Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal
Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal
Premium Pick
WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
Budget Pick
WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical

Top 10 Best Over The Counter Skin Numbing Cream

We researched and compared the top products in the Best Over The Counter Skin Numbing Cream category to provide you with these recommendations.

1. WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical

WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
9.1

Welmate

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  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.

2. Numbing Cream Maximum Strength: Long Lasting Extra Relief with Menthol Arnica and Emu Oil 60ml

Numbing Cream Maximum Strength: Long Lasting Extra Relief with Menthol Arnica and Emu Oil 60ml
7.9

Nupharmco

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  • EXTRA LASTING RELIEF: This numbing cream is provide long-lasting numbing, and relief itching, soreness, burning, and reduce swelling. helps to desensitize the skin, allowing you to feel more comfortable
  • FAST ACTION: We made with special compatibility technology, greatly improving the numbing speed of traditional anesthetic creams. This will reduce your waiting time.
  • EFFECTIVE HEALING PROPERTIES: Our numbing cream contains a blend of powerful ingredients, including Arnica, and Emu Oil, to help speed up the healing process of your skin. This Numbing Cream penetrates the skin to deliver these ingredients, helping to soothe, moisturize, and heal your skin. This means less scabbing and less chance of infection.
  • ODOR-FREE, OIL-FREE & NON-GREASY: Our numbing cream is easy to apply and remove, leaving no mess behind. and contains no harsh chemicals.
  • EASY TO USE: Just wash the area to be treated, apply the numbing cream, and wait for the peak. We recommend patch testing before use to ensure compatibility with your skin.

3. WELMATE 5% Lidocaine Cream for Hemorrhoids, 6 oz Jar – Fast-Acting Lidocaine Numbing Cream &

  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.

4. tuiwaro Numbing Cream Extra Strength: Relief Long Lasting & Fast-Absorbing with Emu Oil and Arnica

tuiwaro Numbing Cream Extra Strength: Relief Long Lasting & Fast-Absorbing with Emu Oil and Arnica
9.1

Tuiwaro

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  • EXTRA STRENGTH, LONG-LASTING RELIEF Fast-absorbing formula delivers lasting comfort for hours* without greasy residue. *Individual results may vary.
  • EMU OIL + ARNICA Skin-calming botanicals to condition and soothe the feel of skin.
  • LIGHT CREAM-GEL TEXTURE Deep yet lightweight absorption; smooth, even glide; no sticky feel, no stains on clothes.
  • EASY, PRECISE APPLICATION Black tube with safety seal and narrow tip for mess-free, even layers; a little goes a long way; 50 mL (1.7 fl oz).
  • FOR DAILY SKIN CARE Use before or after at-home beauty routines; suitable for face & body (external use only). Patch test recommended.

5. Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal

Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal
9.5

Dr Care

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  • BEST NUMBING CREAM Designed for deep skin Numbing and comfort, Dr. Care Tattoo Cream helps prepare skin for tattoos and other beauty treatments.
  • SKIN-SOOTHING INGREDIENTS Contains Emu Oil, Arnica, Aloe vera and vitamin E to calm and support the skins natural balance, plus Aloe Vera and Vitamin E for hydration and softness.
  • MULTI-PURPOSE CREAM Ideal for tattoos, microblading, laser hair removal, waxing, and more; provides a soothing effect before, during and after treatment.
  • FAST-ABSORBING, NON-GREASY FORMULA Smooth, clean application with no sticky residuegreat for professional and at-home use.
  • GENTLE & VEGAN-FRIENDLY Free from harsh chemicals, cruelty-free, and suitable for all skin types. A must-have for your tattoo or cosmetic prep routine.

6. Ebanel Set of 5% Lidocaine Numbing Cream and 5% Lidocaine Spray Pain Relief Numbing Spray for Skin,

  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream and spray with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
  • 5% Lidocaine Cream and Spray Maximum Strength - This pain relief anti itch cream and spray provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Enhanced Liposomal Deep Penetrating Skin Numbing Cream and Pain Relief Spray - Best efficacy, fast-acting & long-lasting. It begins numbing in 2-5 minutes, peaks after 10-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
  • Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

7. AneCream 4% Lidocaine Cream - Topical Lidocaine Numbing Cream - Over-The-Counter Topical Numbing

  • FAST ACTING 4% LIDOCAINE CREAM AneCream is a non-greasy over-the-counter topical lidocaine cream specially formulated with soothing agents. Designed for anesthetic use on normal intact skin to relieve itching and minor cuts and scrapes, its provides relief that lasts for ~ 60 minutes.
  • OTC PAIN RELIEF CREAM It is your essential OTC pain reliever, perfect for every household's first-aid kit. Keep it within reach whether you're on a cruise ship, in your apartment, dorm room, or even on the road with a first aid kit for your car, it is a must-have in your essentials. It is ideal for travel kits and mini purse essentials, ensuring you're always prepared.
  • COOLING Feel the instant cooling effect of AneCream topical numbing cream, whether its a bug bite or a long day in the sun, AneCream is known to have a calming effect on the skin that helps reduce itchiness and inflammation.
  • ANTI-ITCHING Don't let bug bites ruin your day. AneCream, fortified with 4 % Lidocaine, offers fast-acting calming relief, ensuring you can enjoy your time outdoors without discomfort.
  • CHILD-PROOF AneCream 4% lidocaine numbing cream comes equipped with a child-proof lid. No worries about the kiddos getting into any shenanigans because the child-resistant cap keeps em out. Keep your home safe and secure with this added layer of protection.
  • SPORTS ESSENTIAL PERFORMANCE AID AneCreams lidocaine cream is an essential companion for athletes, designed to provide fast-acting ease for sore body tissue, minor injuries, & irritations using its powerful 4% lidocaine blend. Its non-greasy, easy-to-apply texture ensures you apply it exactly where needed. Compact & portable, this lidocaine cream for pain fits everywhere, making it easy to carry wherever you go, hitting the gym, playing on the field, or traveling for competitions,

8. Ebanel 5% Lidocaine Numbing Cream, Pain Relief Cream Burn Itch Cream, 2-Pack Topical Anesthetic

  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
  • 5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
  • Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

9. Adellina Numbing Cream Maximum Strength: Long Lasting Extra Soothing with Arnica and Emu Oil 2OZ/

  • Maximum Strength Formula X5 Numbing- Designed to provide a soothing, cooling sensation on contact for enhanced comfort.
  • Infused with Natural Botanicals - Contains Arnica and Emu Oil, Known for their skin conditioning and calming properties.
  • Cooling and Fast-Absorbing - Lightweight, non-greasy formula that absorbs quickly for temporary comfort.
  • Lightweight & Non-Irritating: Odor-free, oil-free formula glides on smoothly without greasy residue or harsh chemicals for mess-free application.
  • Made in a GMP-Certified Facility - Quality assured and crafted with skin-friendly ingredients.

10. WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical

WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
9.5

Welmate

Check Price On Amazon
  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.

Peter

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