With so many Best Mouthguard Cleaner brands on the market – from prominent names like M3 Naturals,efferdent,EcoBasic,Retainer Brite,KKEKKE to smaller manufacturers – making the right choice can feel overwhelming. But we’re here to help simplify your search for the best product.
We extensively tested and evaluated dozens of top-rated Best Mouthguard Cleaner across various price points, spending over 100 hours comparing the contenders side-by-side. Based on our in-depth first-hand research, we compiled this list of stand-out Best Mouthguard Cleaner to consider. Our top recommendation is M3 Naturals Best Mouthguard Cleaner for its uncompromising quality and performance.
Below you’ll discover more of our favorite Best Mouthguard Cleaner picks. And be sure to consult our buying guide for expert insights on selecting the ideal product for your individual needs and budget. With us guiding your decision, you can shop confidently knowing you’ve chosen an exceptional Best Mouthguard Cleaner you’ll truly love.
Editor's Choice
Retainer Cleaner Tablets Invisalign Cleaner - FSA HSA Approved - Remove Odors Discoloration Stains
Premium Pick
Polident 3 Minute Antibacterial Dental Appliance Cleanser Tablets, 60 Count
Budget Pick
Retainer Brite - Retainer Cleaner Tablets for Invisalign, Mouth Guard Cleaner, Night Guard Cleaner
Top 10 Best Mouthguard Cleaner
We researched and compared the top products in the Best Mouthguard Cleaner category to provide you with these recommendations.
1. Retainer Cleaner Tablets Invisalign Cleaner - FSA HSA Approved - Remove Odors Discoloration Stains
- M3 Naturals Extra Strength Cleaning Tablets are laboratory tested working to restore clarity by removing unwanted odor and buildup in every corner of any oral dental appliance and denture bath*.*
- 120 Tablets of Optimal Results: Our individually wrapped cleaning denture bath tablets provide the most complete cleansing solution on the market. Restore clarity to any dental appliance by removing discoloration, stains, plaque, stubborn odors, and tartar! *
- All Dental Appliances: Our tablets are perfect for denture baths, retainers, aligners, Invisalign, mouth guards, night guards, snore guards, sport, TMJ devices and all other removable dental appliances! *
- Easy to Use: Just drop one tablet into warm tap water along with your dental bath appliance and let our extra strength cleanser do the rest! Quickly restore any dental appliance in just minutes! *
- Soaking Daily in a denture bath is highly recommended and will provide you with the best results by preventing food particle, cloudy film, and plaque buildup. *
2. Efferdent Retainer Cleaning Tablets, Denture Cleaning Tablets for Dental Appliances, Minty Fresh &
- Use Efferdent retainer cleaner tablets daily to clean retainers, full-plate dentures, partials, aligners and other dental appliances
- Kills 99.99% of odor-causing bacteria in 3 minutes while being gentle and non-abrasive
- Efferdent Minty Fresh & Clean antibacterial cleaner tablets cleanse dental appliances while giving them a minty fresh flavor
- Efferdent Fresh & Clean Minty Fresh denture and retainer cleaning tablets use powerful oxi-action to remove stubborn stains in hard-to-reach places
- Efferdent retainer cleaner tablets fight plaque build-up and kill odor-causing bacteria leaving dental appliances fresh and ready-to-use
- Contains 1 box of Efferdent Retainer Minty Fresh & Clean Tablets, 126 Tablets
- Contains 1 pack of Efferdent Fresh & Clean Denture Cleanser, 126 tablets
3. Ultrasonic Retainer Cleaner, Retainer Cleaner Machine for Dentures, Mouth Guards, Braces, Toothbrush
- Advanced Ultrasonic TechnologyThe Ultrasonic Retainer Cleaner employs high-frequency 45kHz sound waves, effortlessly removing dirt from retainers, mouth guards, and dental appliances, reaching all the hard-to-clean corners and crevices without causing any harm to them. Opt for EcoBasic for an efficient cleaning experience, offering 360comprehensive stain removal
- 4 Upgraded UV LightsEquipped with 4 efficient UV lights, 360 all-round deep cleaning, not only Ultrasonic Retainer Cleaner provides excellent cleaning results, but also effectively removes odors. Provide more effective and thorough cleaning, so that the items look new and exude a fresh breath!
- 4 Professional Cleaning ModesRetainer Cleaner Machine has 4 cleaning modes -- . 5 minutes retainer cleaning with UV light; . 10 minutes pulsed retainer cleaning with UV light; . 10 minutes of ultra sound without UV Light; . 10 minutes UV without ultrasound. According to the properties of the item, the appropriate mode is set to achieve the perfect cleaning effect, and the combined use of cleaning tablets is better
- Unique Design of Low Noise The top of the Retainer Cleaner Machine is designed with 2 multi-functional reserve holes, which is very convenient to clean long items such as toothbrush head and makeup brush, and can also be used as a vent to maintain good heat dissipation effect. The bottom is equipped with four pieces of non-slip rubber, which is easy to stabilize the Retainer ultrasonic machine, effectively reduce noise and make it safer to use
- Large Capacity & PortableCleaner Machine is portable, 200ml large capacity enough to clean dentures, braces and other items, suitable for travel with; There are also a shelve and tweezer for easy cleaning of jewelry or waterproof watches. This Denture Cleaner Machine is also a great gift for seniors and adults
- For All Dental ToolsThis Ultrasonic Retainer Cleaner is extremely simple to operate and can clean all dental tools with one-button control. Denture Cleaner is the ideal gift for family and friends! EcoBasic provides excellent customer service, if you have any questions or concerns, please contact us!
4. Retainer Brite - Retainer Cleaner Tablets for Invisalign, Mouth Guard Cleaner, Night Guard Cleaner
- Retainer Brite's cleaning tablets keep your clear retainers, aligners, wire retainers, sports mouthguards, and nightguards clean and odor-free
- Intended for patients who use removable dental appliances - not for artifical teeth or partial dentures
- Easy to use and fast acting
- Soak your dental appliances daily for the best results
- Package includes 120 individually wrapped tablets (4 month supply) to keep your appliances clear, bright and fresh
5. Efferdent Retainer Cleaning Tablets, Denture Cleanser Tablets for Dental Appliances, Complete Clean,
- Use Efferdent retainer cleaner tablets daily to clean retainers, full-plate dentures, partials, aligners and other dental appliances
- Kills 99.99% of odor-causing bacteria in 3 minutes while being gentle and non-abrasive
- Efferdent Complete Clean antibacterial cleaner tablets provide an everyday, odor-free clean
- Efferdent Complete Clean denture and retainer cleaning tablets use powerful oxi-action to remove stubborn stains in hard-to-reach places
- Efferdent retainer cleaner tablets fight plaque build-up and kill odor-causing bacteria leaving dental appliances fresh and ready-to-use
- Contains 1 box of Efferdent Retainer Complete Clean Tablets, 126 Tablets
- Contains 1 pack of Efferdent Coffee & Tea Denture Cleanser, 126 tablets
6. Ultrasonic Retainer Cleaner, 45kHz Retainer Cleaner Machine for Dentures, Mouth Guards, Aligner,
- Highly Efficient Retainer Cleaner: Our ultrasonic retainer cleaner uses 25W high-efficiency power and 45kHz frequency technology to provide 360-degree deep cleaning for braces, dentures, retainers, dental aligners, and mouth guards. Its gentle yet efficient cleaning function is also suitable for delicate items such as jewelry, rings, waterproof watches, etc. Easily remove stubborn stains and hard-to-reach corners without damaging valuables. Use with cleaning tablets, mouthwash, or professional solution for better results
- 4 Professional Cleaning Modes: This retainer cleaner machine combines ultrasonic and LED dual cleaning technology with 4 cleaning modes: 1. Green Light: 5 min (300 sec) ultrasonic cleaning with LED light; 2. Red Light: 10 min (600 sec) pulse ultrasonic cleaning with LED light; 3. Blue Light: 10 min (600 sec) ultrasonic cleaning without LED light; 4. All Lights On: 10 min (600 sec) LED cleaning without ultrasonic. The cleaning process can be flexibly adjusted to suit your needs. The LED light not only removes stubborn dirt but also eliminates odors
- Low Noise Design: The unique low-noise design(40dB) of the night mouth guard cleaner brings you a quiet cleaning experience. The top of the retainer cleaner is designed with 2 multi-functional reserved holes, which is very convenient for cleaning long items such as toothbrush heads and makeup brushes, and can also be used as vents to maintain good heat dissipation. The digital timing display can show the remaining time, and the bottom is equipped with a non-slip rubber pad to ensure that the device is stable and safe during operation
- Portable and Robust Materials: This ultrasonic retainer cleaner is small and lightweight, making it perfect for home, office, or travel use. It measures 4.33x4.33x3.82 inches and weighs less than 1 pound. It is equipped with a 200ml stainless steel inner tank and uses a sturdy ABS shell, which is waterproof and robust. It comes with tweezers and a basket for easy cleaning of small items, making it safe and convenient for daily use
- Easy and Fast Operation: The energy-saving design reduces energy consumption, and the one-button operation is simple and easy to use. For stubborn stains, it works better with cleaning liquid, but it works just as well with water. After use, just pour out the water and wipe dry with a towel for easy maintenance. The modern and stylish design of this ultrasonic denture cleaner is an ideal gift for the elderly, family, friends, and loved ones. The product comes with a 1-year warranty and 24/7 customer service support, so you can use it with peace of mind
- NOTE: Ensure the water level covers the minimum fill line inside the tank but does not exceed the maximum fill line.
7. Dental Ultrasonic Retainer Cleaner Machine - Dental Cleaning Pod for Denture, Mouth Guard, Aligner,
- ADVANCED ULTRASONIC TECHNOLOGY: Experience clinical-grade cleaning right at home with the UEOFEN retainer cleaner machine. Utilizing high-frequency 45000Hz ultrasonic vibrations to generates millions of nano-scale bubbles, it penetrates deep into every gap and hard-to-reach areas, thoroughly and gently removing stains from dental appliances. Give your retainers, dentures, mouth guards, braces, night guards toothbrushes and jewelry a brand new look effortlessly.
- EFFICIENT 254NM UV LIGHT: Equipped with 4 powerful 254nm UV lights, our retainer cleaner effectively provides a higher level of cleanliness while removing unpleasant odors to keep your dental appliances clean and fresh. It can also be used in conjunction with cleaning tablets to tackle stubborn stains and odors for more superior cleaning results. (Note: Cleaning tablets are not included.)
- DUAL CLEANING MODES: The ultrasonic retainer cleaner features dual cleaning modes that can be easily switched by pressing a button: I.Quick 5-minute clean with ultrasonic cleaning and UV light. II. Deep 10-minute clean with ultrasonic pulse cleaning and UV light. The 10-minute cleaning mode works for 2 seconds and pauses for 1 second to enhance the cavitation effect of ultrasonic cleaning and achieve more thorough cleaning effect.
- CONVENIENCE & USER-FRIENDLY DESIGN: Say goodbye to the hassle of manual cleaning! This dental cleaning pod is easy to use, allowing you to maintain your dental instruments effortlessly. With a digital timer on top, keep track of your cleaning progress with the countdown feature. Two multifunctional ports are very convenient for cleaning items with handles such as toothbrushes. It also comes with a tweezer for easy entry and removal of items.
- 200ML CAPACITY & LOW NOISE: Designed with a large 200ML capacity, the denture cleaner fits dental appliances of any size. Its compact size will not take up much space on the counter, and it is also easy to carry and suitable for travel. In addition, it runs quietly below 45dB, offering a quiet cleaning experience without disturbing your surroundings.
- WORRY-FREE AFTER-SALES: With its powerful cleaning ability and sleek appearance, the ultrasonic cleaner is also an ideal choice as a gift for family and friends. We promise to provide a 30-day refund policy and a 24-month warranty. Your satisfaction is our top priority - please contact our professional after-sales support team for assistance.
8. 2025 Ultrasonic Retainer Cleaner for Dentures & Aligner, Durable Removable Base and Top Cover,
- 2025 Advanced Ultrasonic Cleaner + U-V Lights = 100% Clean!This ultrasonic cleaner uses 42kHz ultrasonic waves and rich bubbles to scrub away stains and plaque while being non-abrasive to your dental appliance. Combined with u-v lights, the retainer cleaner provide a deep and 360 all-round cleaning for retainers, mouth guard, jewelry, rings and brushes, etc
- Unique Tank-Base Design - Use it for YEARSThe cleaner tank can be remove from the base, which is easily to be cleaned by water without risk of electric shock. Other cleaners usually broken within just 2 months! Haneuul cleaner machine is much durable than the others! Use it for years is not a problem!
- Widely Application for Premium CleaningTwo large openable windows on the top are designed for placing toothbrushes, make up brushes and any long appliances. Windows can also be used as a vent to maintain good heat dissipation effect, and its good for you to see the inside status. The bottom is equipped with non-slip rubber, which is easy to stabilize the retainer ultrasonic tank, effectively reduce noise level to use
- Fresh, Healthy, SimpleSimple operation with two buttons, be fresh cleaned within minutes! Three timer set (5/8/10 minutes) for different needs of cleaner. Independent button for u-v lights, easy to turn on/off lights. The cleaner comes with a tray, a brush and a tweezer for easy cleaning of retainer, jewelry and rings
- Top Quality & Customer Support with Bold CommitmentHaneuul has sold 10+ million ultrasonic cleaners worldwide and is always committed to providing first-class quality and service. Your purchase comes with a 30-day free return and hassle-free 365-day warranty (FREE replacement and no fees required. Just contact us). Plus, we offer pro support thats available 24/7, providing you with dedicated 1-on-1 support
- Preferred by 96% Aligner Users!Our ultrasonic denture cleaner has been widely used by aligner users and top-rated dentist and doctors all around the world. This denture cleaner is the perfect thoughtful gift for kids, wives, husbands, mom and dad, and your beloved family members.
9. Aotuda 45kHz Ultrasonic Retainer Cleaner Machine, 200ML Denture Cleaner, 4 Modes with Digital Timer
- Preferred by Most Aligner Users: Our Ultrasonic Retainer Cleaner uses powerful 45 kHz sound waves and 25W power to provide a deep and gentle 360 clean for all dental appliances, over 95% aligner users confirmed that the 25W setting provides the most effective cleaning without causing any harm
- Latest Technology Cleaning: The retainer cleaner can generate millions of tiny cleaning bubbles, penetrating crevices and grooves, also comes with 4 LED U-V lights that helps to providing a level of cleanliness that surpasses toothbrush. Gives your retainers, braces, dentures, night guard, or mouth guard cleaner a fresh makeover
- 4 Specialized Cleaning Modes: Ultrasonic denture cleaner featuring 4 modes with one button control, digital time display 5 Min/10 Min (300 seconds/600 seconds) and indicator light : 1. green light: ultrasonic+u-v clean, 2. red light: pulse+u-v clean, 3. blue light: ultrasonic clean, 4 all light on: u-v clean. Different cleaning process to suit your dentures' needs, enhance the cleaning effectiveness by pairing with cleaning tablets or mouthwash
- Utility & Made to Last: Retainer cleaner machine is built from ABS plastic or insulated SUS 304 stainless steel, which makes it both firm and safe. Ensure 200 ml capacity but very compact for on-the-go use(size: 4.72*4.72*4.21 in, weighs: 0.73 lb). Also equipped with a basket and tweezers as jewelry cleaner, for easy cleaning of jewelry or waterproof watches
- Environmentally Conscious: Our dental aligner cleaner pod uses only one tiny motor, providing minimum energy consumption. Compared to the energy used when scrubbing your appliances, this cleaning machine is much better for environment. It's also an excellent gift for those who value cleanliness and hygiene and is even appreciated by environmentalistsPackage List1*Ultrasonic Retainer Cleaner, 1*DC Power Adapter, 1*User Manual, 1*Tweezers, 1*Mesh Basket, there is no solution or tablets
- Important Note: We offer a 1-year upkeep service and a 30-day hassle-free return/exchange policy. If you encounter any problems or concerns, please get in touch with us and we will be at your service 24 hours a day! (1)Please don't connect the power supply before adding water, keep the power connector dry to prolong the machines life. (2)Please don't use other types of power cords, make sure the machine is used under 110 V, otherwise it will be damaged. (3) If your devices have never been cleaned before, please use cleaning tablets or cleaning solution together for better results
10. Polident 3 Minute Antibacterial Dental Appliance Cleanser Tablets, 60 Count
- 60 count of Polident 3 Minute Antibacterial Dental Appliance Cleanser Tablets
- New improved formula (1) with more active power bubbles (1) that clean even the hardest to reach places (2)
- This retainer cleaner (3) kills 99.9% of odor-causing bacteria (2) and keeps your dental appliance fresher for longer (5)
- Our denture cleaner is specially designed formula for dental appliances including full dentures, partial dentures, retainers, aligners, and mouthguards (3)
- Active power bubbles are tough on dirt but gentle on your dental appliance for a 360-degree deep clean (4)
- Easy to use -just soak, brush, rinse (4), and go!
- Polident is the #1 Dentist Recommended Dental Appliance Cleansing Brand
Peter
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