Best Microneedling Numbing Cream

Peter | 26-12-2025

With so many Best Microneedling Numbing Cream brands on the market – from big names like Ebanel,Dr Care,WELMATE,Subleef,HealthWise to smaller companies – finding the right product can be a real challenge. But we’re here to make your search easier.

We carefully researched and tested a vast range of Best Microneedling Numbing Cream to help you discover the top contenders that match different needs and preferences. Altogether, we spent over 100 hours evaluating numerous products first-hand.

Our #1 best Best Microneedling Numbing Cream is Ebanel Best Microneedling Numbing Cream, based on its stellar performance across all our tests. Below you’ll find more of our top-rated recommendations for great Best Microneedling Numbing Cream options currently available. Make sure to check out our buying guide too – it’s full of expert advice for choosing a Best Microneedling Numbing Cream tailored to exactly what you’re looking for. With our help guiding your decision, finding your perfect fit will be a breeze!

Editor's Choice
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical
Premium Pick
Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal
Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal
Budget Pick
WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical

Top 10 Best Microneedling Numbing Cream

We researched and compared the top products in the Best Microneedling Numbing Cream category to provide you with these recommendations.

1. Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical

  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
  • 5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Enhanced Liposomal Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
  • Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

2. Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal

Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal
9.5

Dr Care

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  • BEST NUMBING CREAM Designed for deep skin Numbing and comfort, Dr. Care Tattoo Cream helps prepare skin for tattoos and other beauty treatments.
  • SKIN-SOOTHING INGREDIENTS Contains Emu Oil, Arnica, Aloe vera and vitamin E to calm and support the skins natural balance, plus Aloe Vera and Vitamin E for hydration and softness.
  • MULTI-PURPOSE CREAM Ideal for tattoos, microblading, laser hair removal, waxing, and more; provides a soothing effect before, during and after treatment.
  • FAST-ABSORBING, NON-GREASY FORMULA Smooth, clean application with no sticky residuegreat for professional and at-home use.
  • GENTLE & VEGAN-FRIENDLY Free from harsh chemicals, cruelty-free, and suitable for all skin types. A must-have for your tattoo or cosmetic prep routine.

3. WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical

WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
9.1

Welmate

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  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.

4. Subleef Deep Numbing Cream Maximum Strength, Long Lasting Topical Anaesthetic Cream Relief Pain

Subleef Deep Numbing Cream Maximum Strength, Long Lasting Topical Anaesthetic Cream Relief Pain
8.9

Subleef

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  • Maximum Strength Active Ingredient: Our topical numbing cream is formulated with the highest non-prescription active ingredient percentage available . It penetrates deep to block nerve signals, providing powerful and effective relief from pain, itching, and burning sensations
  • Gentle & Fast-Acting Formula: Our cream is carefully crafted to be effective yet gentle on the skin. It absorbs quickly to start working where you need it most, providing a soothing barrier that minimizes procedural discomfort.
  • GMP Certified Manufacturing: Every batch is produced under strict Good Manufacturing Practice (GMP) guidelines. This certification is your assurance of a product that meets the highest possible standards for safety, consistency, and quality, trusted by professionals and enthusiasts alike
  • Versatile Pain Relief Cream: This cream is a must-have for anyone undergoing cosmetic or personal care procedures for relief from minor skin irritations, burns, or insect bites . It's trusted by anyone with sensitive skin
  • We are so confident in the power of our numbing cream that we offer a risk-free guarantee if you are among the extremely rare few who do not achieve the desired deep numbing effect.

5. HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy
8.9

Healthwise

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  • MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • FAST-ACTING LIDOCAINE Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
  • SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Aspercreme with Lidocaine active ingredients
  • 2.7 oz. bottle (49.6g)

6. WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical

WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
9.5

Welmate

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  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.

7. Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Numb25 Topical

  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
  • 5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
  • Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

8. WELMATE 5% Lidocaine Cream for Hemorrhoids, 6 oz Jar – Fast-Acting Lidocaine Numbing Cream &

  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.

9. Clinical Resolution Numb Master 5% Lidocaine Numbing Cream for Pain Relief, Topical Anesthetic Burn

Clinical Resolution Numb Master 5% Lidocaine Numbing Cream for Pain Relief, Topical Anesthetic Burn
8

Clinical Resolution

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  • 5% TOPICAL LIDOCAINE PAIN RELIEF 5% Lidocaine Numbing Cream Maximum Strength Topical Pain Relief - This anti burn itch cream provides rapid pain relief for minor aches, minor cuts, minor scrapes, sunburn, scrapes and minor skin irritations. It also works for mosquito bite itch relief, bug bite itch relief, insect bite relief, postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders.
  • LONG LASTING & QUICK RELIEF - Enhanced Liposomal Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
  • NON-OILY & NON-GREASY - Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal.
  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

10. Curist 5% Lidocaine Cream Topical Pain Relief - Numb Quickly & Effectively with 5% Lidocaine Numbing

  • LIDOCAINE 5% PAIN CREAM | Experience deep pain relief with the strongest formulation of topical lidocaine available OTC.
  • A fast pain relief, anti itch, and numb cream - made with the highest quality ingredients without the typical pharmacy mark-up.
  • TREAT, NUMB & SOOTH ALL-IN-ONE | Our soothing, numbing cream provides fast relief from pain, itching, burning, discomfort & irritation by blocking the nerves and desensitizing. Numbing relief for hemorrhoids and other anorectal issues.
  • CURIST PAIN RELIEF CREAM | Stronger tha Aspercreme 4% Lidocaine, which is typically used for muscle pain and as a numbing cream.
  • EASY ACCESS JAR | Light, whipped formula for easy application. Get numbing relief at a fraction of the cost. For external use only.

Peter

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