Best L Methylfolate Supplement

Peter | 26-06-2025

If you aren’t someone who makes frequent purchases, selecting the best Best L Methylfolate Supplement won’t be an easy chore for you. However, you shouldn’t be concerned because we have provided you with the most comprehensive list possible of the top Best L Methylfolate Supplement. Have a look at the products on our list, and pick the ones that appeal to you the most.

We researched and tested Best L Methylfolate Supplement in the market to get you this list. Our most recommended product is Carlyle Best L Methylfolate Supplement. Check out our picks for all of our favorites, and be sure to read our buying guide to get all the information you need to make the best choice!

Editor's Choice
L Methylfolate 15mg | 120 Capsules | Value Size | Max Potency | Optimized and Activated | Non-GMO,
L Methylfolate 15mg | 120 Capsules | Value Size | Max Potency | Optimized and Activated | Non-GMO,
Premium Pick
L Methylfolate 7.5 mg | 60 Capsules | Optimized and Activated | Non-GMO, Gluten Free | Methyl
L Methylfolate 7.5 mg | 60 Capsules | Optimized and Activated | Non-GMO, Gluten Free | Methyl
Budget Pick
NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90
NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90

Top 10 Best L Methylfolate Supplement

We researched and compared the top products in the Best L Methylfolate Supplement category to provide you with these recommendations.

1. L Methylfolate 15mg | 120 Capsules | Value Size | Max Potency | Optimized and Activated | Non-GMO,

L Methylfolate 15mg | 120 Capsules | Value Size | Max Potency | Optimized and Activated | Non-GMO,
9.8

Carlyle

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  • L-METHYLFOLATE: A metabolically active form of Folic Acid, also known as Folate or B-9 Vitamin!
  • COMPLETE FORMULA: Quick-release capsules deliver 25,000 mcg Folate (15 mg L-METHYLFOLATE)
  • ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living.
  • CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
  • NATURALLY FREE OF: Gluten, Wheat, Yeast, Lactose, Soy, Artificial Flavor, Preservatives and Non-GMO

2. L Methyl Folate 15mg Plus Methyl B12 Cofactor – Organic Berry Flavor, High Potency Liquid

L Methyl Folate 15mg Plus Methyl B12 Cofactor – Organic Berry Flavor, High Potency Liquid
9.5

Triquetra Health

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  • HIGH-POTENCY: Provides a high-potency serving of 15mg L-Methylfolate in the 5-MTHF calcium salt form. This bioactive form of folate is readily utilized by the body.
  • VITAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships that work together in the body's methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.
  • ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is immediately absorbed into the bloodstream because it does not require processing or breakdown by the body. This is vital for those with methylation issues that cannot properly process folic acid.
  • SUPPORTS BRAIN, MOOD & ENERGY HEALTH: Important for healthy neurotransmitter function linked to focus, energy, and a balanced mood.
  • SUPPORTS CARDIOVASCULAR, NITRIC OXIDE & NERVE HEALTH: Helps maintain healthy homocysteine levels, promotes normal heart function, and supports nitric oxide production for overall circulatory and nerve well-being.

3. Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO,

Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO,
8.9

Life Extension

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  • BIOLOGICALLY ACTIVE FOLIC ACID Our Optimized Folate formula promotes both cardiovascular and cognitive health with 1700 mcg of folate in the form of 5-MTHF (L-Methylfolate), the metabolically active form of folic acid.
  • WHY FOLATE? Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with heart and brain health. Folate, a B vitamin, helps maintain homocysteine levels already within normal range. However, not everyone can efficiently convert folate to its biologically active form. Our formula provides 5-MTHF, so you dont have to.
  • HEART & BRAIN-FRIENDLY NUTRIENT Because folate helps inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular biomarker. Since healthy homocysteine levels have been associated with cognitive health, getting enough folate is especially crucial for individuals who want to maintain brain health.
  • INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free, and manufactured in the USAand a Certificate of Analysis is available for every product we produce.
  • LIVE YOUR HEALTHIEST LIFE - For over 40 years, weve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. Our formulations are created using the ingredients and dosages used in the studies that inspired them, ensuring that maximum bioavailability and efficacy is achieved.

4. Thorne 5-MTHF 1mg - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health,

  • Healthy Methylation: A breakthrough in active folate supplementation for healthy methylation*
  • Positivity: Supports a healthy outlook*
  • Nerves & Circulation: Supports healthy blood vessel and nerve function*
  • Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health*
  • Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams

5. L Methylfolate 7.5 mg | 60 Capsules | Optimized and Activated | Non-GMO, Gluten Free | Methyl

L Methylfolate 7.5 mg | 60 Capsules | Optimized and Activated | Non-GMO, Gluten Free | Methyl
9.8

Carlyle

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  • Gluten Free, Non-GMO; Free Of Wheat, Yeast, Milk, Lactose, Soy, Artificial Color, Artificial Flavor
  • Each L-Methylfolate (5-MTHF) capsule provides you 7.5mg of this bioavailable form of folic acid
  • Folate, also referred to as Folic Acid, is a fully active B complex vitamin; 12,500mcg DFE of Folate
  • Our professional formula is backed by our commitment to purity and potency
  • Manufactured in a facility that is GMP certified

6. Nutricost Methylfolate 1000mcg, 120 Vegetarian Capsules - Gluten Free, Non-GMO

Nutricost Methylfolate 1000mcg, 120 Vegetarian Capsules - Gluten Free, Non-GMO
8.5

Nutricost

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  • 120 Capsules MethylFolate (120 Servings)
  • 1,000mcg MethylFolate Per Serving
  • Vegetarian Capsules
  • Non-GMO & Gluten Free & 3rd Party Tested
  • Made in a GMP Compliant, FDA Registered Facility

7. NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90

  • CO-ENZYME B VITAMIN/1,000 mg TABLETS: Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA.
  • METABOLICALLY ACTIVE FOLATE/SUPERIOR BIOAVAILABLITY: Quatrefolic is a patented form of methylfolate that has demonstrated bioavailability superior to that of folate from dietary sources.
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Vegan/Vegetarian
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968

8. NatureBell L Methylfolate 15mg, 240 Veggie Capsules | 5-MTHF with Methyl B12 1,000mcg | High Potency

NatureBell L Methylfolate 15mg, 240 Veggie Capsules | 5-MTHF with Methyl B12 1,000mcg | High Potency
7.7

Naturebell

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  • High Potency Dual Action: Powerful combination of Methyl Folate 15mg and Vitamin B12 for enhanced energy and cognitive support, promoting overall health and well-being.
  • Active Folic Acid - L-methylfolate: Easily absorbed for maximum benefits in mental clarity, cognitive function, prenatal health.
  • 240 Vegetarian Capsules: 4-month supply of premium quality, gluten-free, non-GMO vegetarian capsules, suitable for those with dietary restrictions.
  • Energy & Cognitive Health: Supports normal energy metabolism, reduces fatigue, and maintains healthy neurological function for optimal mental performance and focus.
  • Trusted Quality & Purity: Certified by 3rd party labs, ensuring the highest quality standards and ingredient purity for a premium and effective supplement.

9. L Methylfolate 7.5mg plus Methyl B12 - Active 5-MTHF Form, MTHFR Supplement - Bloodstream Ready

L Methylfolate 7.5mg plus Methyl B12 - Active 5-MTHF Form, MTHFR Supplement - Bloodstream Ready
7.9

Triquetra Health

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  • DAILY DOSE of 7.5 MG L METHYL FOLATE : Provides dose of 7.5mg L Methylfolate in the 5-MTHF calcium salt form. This is the most active form of Folate.
  • ESSENTIAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships. Both are crucial in the body's methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.
  • ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is immediately absorbed into the bloodstream because it does not require processing or breakdown by the body. This is crucial for those with methylation issues that cannot properly process folic acid.*
  • BRAIN, MOOD & ENERGY SUPPORT: Essential to neurotransmitters production involved in concentration, sleep, energy, hormones & mood.*
  • CARDIOVASCULAR, NITRIC OXIDE & NERVE SUPPORT: Supports heart health and nerve function by supporting healthy homocysteine levels and nitric oxide production.
  • MADE IN USA, cGMP MANUFACTURING, 3rd-PARTY LAB TESTED: Triquetra Health adheres to the highest quality standards. All products are proudly made in the USA with the purest, most clinically backed ingredients. They are produced in cGMP and certified organic facilities. And they are 3rd party lab-tested to ensure potency, purity, and quality.

10. MethylPro 15mg L-Methylfolate (90 Capsules) - Professional Strength Active Methyl Folate, 5-MTHF

MethylPro 15mg L-Methylfolate (90 Capsules) - Professional Strength Active Methyl Folate, 5-MTHF
8.7

Methylpro

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  • The Leader In Faster, Active Folate - Approximately half the US population may have difficulty converting folate into its active form. MethylPro is the leading nutraceutical line featuring l-methylfolate, the most advanced form for better results.*
  • Professional Strength - Many methylfolate products contain mcg or 1mg amounts. MethylPro offers a range of potent therapeutic doses. This 15 mg dose is our strongest, for a difference you can feel.*
  • Brain & Mood Support - Methylfolate is important for the production of neurotransmitters involved in concentration, sleep, energy, hormones and mood stability. This is the only form of folate to cross the blood-brain-barrier.*
  • Promotes Cardiovascular & Nerve Health - May help promote heart health & healthy peripheral nerve function by supporting already healthy homocysteine levels and nitric oxide production.*
  • No Fillers - MethylPro never uses fillers or excipients like bulking agents, glues, or binders. The only additional ingredient is the amino acid glycine. This product is free of soy, gluten, dairy, eggs, and nuts. Take only as directed under the supervision of a Physician.*

Peter

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