Best Enzyme Laundry Detergent

Peter | 26-08-2025

Navigating the many Best Enzyme Laundry Detergent options on the market – from major brands like ACTIVE,Nature’s Miracle,Dirty Labs to lesser-known names – can feel overwhelming. But we’re here to help simplify your search for the best products.

After extensive research testing hundreds of Best Enzyme Laundry Detergent, we’ve selected the top contenders. Our number one recommendation is ACTIVE Best Enzyme Laundry Detergent based on its stellar performance and quality. Below you’ll find more of our top-rated picks for the best Best Enzyme Laundry Detergent currently available.

Be sure to consult our handy buying guide as well for expert tips on choosing the right Best Enzyme Laundry Detergent to suit your individual needs. It has all the crucial information you need to make an informed purchasing decision. With our guidance backing your choice, finding your perfect match will be smooth sailing!

Editor's Choice
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder,
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder,
Premium Pick
Nature's Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Oz., Laundry Stain and Odor
Nature's Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Oz., Laundry Stain and Odor
Budget Pick
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE

Top 10 Best Enzyme Laundry Detergent

We researched and compared the top products in the Best Enzyme Laundry Detergent category to provide you with these recommendations.

1. Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder,

  • Powerful Bio Enzymatic Cleaner: ACTIVE Laundry Odor Removers Boost your normal laundry detergent to effectively target Stains & Odors, not mask them like washing soda or in-wash scent boosters. It uses Lab-proven Biological Cleaning to remove laundry odor & strong smell
  • Heavy Duty Stain Remover for clothes: Our Enzyme Laundry Additive Powder is formulated for Stain Removal of dirty clothes, perfect for Funk, Grease, Armpit Sweat stain, Blood stain, Oil and more!
  • Gentle on All Fabrics: Our Fragrance Free Laundry Boost Plant-based Formula uses zero harsh chemicals. Natural enhancer for whites & colors. Even safe for pesky activewear fabrics
  • Value 64 Load Package: ACTIVE Enzyme Cleaner Concentrated 32-oz size is good for 64 Loads compared to other products with 1 lb or less
  • Compatible with all Washers & Detergents: Add Laundry Booster Powder to your usual detergent & cleaners! HE, Front & Top load Washer Approved. Also use as laundry soak pretreat powder in order to treat set-in stain

2. Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE

  • Concentrated Powder Detergent: ACTIVE Pet Detergent is a Powerful, High Efficiency Compatible Odor Destroyer & Stain Eliminating Detergent. Every Scoop has a Natural Cleaning Power to Handle any Mess, Stain, or Smell left behind by your pet.
  • Suitable for all Pet Laundry: Including Pet Bed, Clothing, Leash, Harness, Blankets, Towels, Furniture Covers & More! ACTIVE is an All-in-One Laundry Detergent Compatible With All Fabric Types, Even Use on your own Clothing and Bedding that smells like your pet!
  • Bio Based Enzyme Cleaner: ACTIVE Enzyme Laundry Detergent is Formulated to Target Pesky Stains and Odors, Including Pet Urine, Cat & Dog Pee, Vomit, Slobber, Dirt, Grime, Oils and Protein Stains. ACTIVE Enzymes even get rid of Wet Dog Odor, and others stubborn scents
  • Natural & Fragrance Free: ACTIVE Pet Detergent is a Natural Laundry Stain Remover, Free of Harsh Chemicals and Gentle for Pets and Sensitive Skin. ACTIVE Actually Removes Odors rather than using scents to cover them up like some alternatives
  • Best Value 64 Loads: Compare ACTIVE Dog Laundry Detergent to liquids that take up more space with less uses. Our Value Pack Comes in a Bulk 2 Lb bag so you can Keep Your Pet Laundry Taken Care Of!

3. Nature's Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Oz., Laundry Stain and Odor

Nature's Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Oz., Laundry Stain and Odor
9.5

Nature's Miracle

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  • LAUNDRY BIO-ENZYMATIC FORMULA: Helps break down and destroy tough pet stains and odors, such as urine, feces, vomit, blood, grass and drool.
  • GENTLE ON FABRICS: Perfect for use on clothing, pet beds and morenot for use on specialty fabrics, including washable silk, khaki, fluorescents, wool, suede and leathers.
  • SAFE FOR PETS AND HOME: Formulated without phosphates, parabens, sulfates and bleach, this product is safe for use around pets and home, when used as directed.
  • ODORCAPTURE 360 TECHNOLOGY: An odor neutralizing system from Natures Miracle, the brand you trust because it works!
  • WORKS IN ALL MACHINES INCLUDING HE: Use in addition to your laundry detergent to help loosen and remove tough pet stains and odors.

4. Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High

Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High
8.3

Dirty Labs

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  • GENTLE: Our formula is consciously formulated with 100% bio and mineral-based ingredients. We left out all the harsh chemicals, fillers, toxins, and pollutants commonly found in other boosters to create a hyperefficient, nontoxic, biodegradable formula. We only use the good stuff so your body and the environment are left as clean as your detergent.
  • EFFECTIVE: Our advanced 4-in-1 formula is the first laundry product in the US to feature a groundbreaking bioenzyme that breaks down tough-to-remove biological stains and odors caused by sweat, body grime, and blood. (Think ring around the collar, yellow pit stains, weird grey or yellow stains on your favorite white sheets, and other stains.)
  • ENVIRONMENTALLY FRIENDLY: At Dirty Labs - Less is More. By creating hyper-concentrated formulas, we greatly reduce our package sizes (and thus, our carbon footprint). Our packaging is made of recyclable cardboard. Our scoop is made from responsibly sourced schima superba wood. Our materials are responsibly sourced and extracted directly from nature. We examine every aspect of our product life cycles in order to achieve the safest, most sustainable solutions.
  • DIRECTIONS: Follow your washer and garment care label instructions. For best results, use with Dirty Labs Bio Laundry Detergents. For standard and HE machines. Septic Safe. 1) Use laundry detergent as you normally would. 2) Add Bio Laundry Booster to wash drum before adding clothes.
  • SPECS: 480 g = 48 loads. Free & Clear (Scent Free). Compatible with traditional and HE washers. Optimized for cold water. No synthetic ingredients. Biodegradable formula. Hypoallergenic and safe for sensitive skin. Safe for babies and pets. Cruelty-free. Vegan. No sulfates. No dyes. No parabens and preservatives. No optical brighteners. No chlorine bleach. No 1,4-dioxane. No fragrance. No CA Prop. 65 chemicals. Packaging and formula are BPA-free.

5. Active Wear Laundry Detergent & Soak - Formulated for Sweat and Workout Clothes - Natural

  • Made in USA - Our powdered detergent is scientifically formulated with all natural plant-based enzymes that remove and eliminate smells generated from sweat in fitness and gym clothes
  • Specialized Formula- The specialized laundry detergent for men's or women's athletic clothing compatible with your favorite brands activewear
  • Workout Clothes Detergent - Remove smells from workout shirts, shorts, bras, tank tops, leggings, yoga pants, uniforms, jerseys, compression underwear, jock strap, and socks
  • Plant Based - ACTIVE is free from SLS free, phosphate free, gluten-free, septic safe. Made with plant based enzymes
  • Save Money - Concentrated formula provides a bulk value of 90 loads per bag! ACTIVE laundry detergent extends your clothes lifespan and protects them for the long run!

6. Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) |

Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) |
8.7

Dirty Labs

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  • GENTLE: Most cleaners today use technologies that were developed almost 100 years ago. In fact, many common deep-cleaning formulas still rely on harmful, petroleum-based chemicals. Dirty Labs is different. Consciously formulated with nontoxic, biobased ingredients, our formulas are safe for sensitive skin and all clothing types. Dirty Labs is cruelty-free, vegan, hypoallergenic, and safe for babies and pets.
  • EFFECTIVE: For us, dirty-free cleaning is not just about clean ingredients. We formulate to get the job done, and we put our products through rigorous testing to ensure theyre strong enough for those who like to get really dirty. Phytolase, our advanced enzyme cleaning technology targets stains and odors at their source while being extra gentle for you, your clothes, and the planet. But don't just take our word for it see what our customers are saying.
  • ENVIRONMENTALLY FRIENDLY: At Dirty Labs - Less is More. By creating hyper-concentrated formulas, we greatly reduce our package sizes (and thus, our carbon footprint). Our bottles are made of aluminum and can be infinitely recycled. Our ingredients are responsibly sourced and created through biorenewable manufacturing processes. We examine every aspect of our product life cycles in order to achieve the safest, most sustainable solutions.
  • DIRECTIONS: Follow your garment care label and washing machine instructions. Measure with teaspoon or Dirty Labs silicone beaker (available separately, or with all 32 load bottles). For tough stains, pretreat directly to soil area and allow to sit for 5 minutes before washing. Our detergent is hyper-concentrated use as follows: 8ml for medium loads, 12ml for large loads, 16 ml for x-large loads.
  • SPECS: 21.6 fl oz = 80 loads. Free & Clear (Scent Free). Compatible with traditional and HE washers. Optimized for cold water. Certified EPA Safer Choice Partner. 97% USDA Biobased certified. No sulfates, dyes, parabens, preservatives, chlorine bleach, or CA Prop.65 Chemicals. Visit our store for more ingredients information.

7. Lysol Tough Odor Eliminator Laundry Sanitizer Additive, Sanitizing Liquid for Gym Clothes and

  • LAUNDRY DETERGENT ADDITIVE: Add Lysol Laundry Sanitizer to every wash, in the fabric softener drawer, to sanitize and deodorize smelly laundry. Lysol Laundry Sanitizer kills many bad odors that detergents leave behind.
  • COLOR SAFE BLEACH ALTERNATIVE: Lysol Laundry Sanitizer is a bleach alternative that effectively kills 99.9% of bacteria***, without the harshness of bleach. It's gentle on fabrics, effective in cold water, and is safe to use on colors and whites.
  • LYSOL LAUNDRY SANITIZER: Better than in-wash scent boosters that just mask bad odors. Lysol Laundry Sanitizer kills the odor causing bacteria that laundry detergents alone can leave behind, even in cold water! Can be used in standard and HE machines.
  • ODOR ELIMINATOR FOR STRONG ODOR: Say goodbye to stubborn odors with Lysol Laundry Sanitizer, an advanced formula designed to act as an effective odor eliminator for even the toughest smells, leaving your clothes smelling fresh after every wash.
  • HOUSEHOLD ESSENTIALS & CLEANING SUPPLIES: Lysol is a leader in disinfection. Shop our range of household cleaning supplies including disinfectant wipes, toilet bowl cleaners, air sanitizers, and disinfectant sprays. The best protection is prevention!
  • ***Kills 99.9% of Staphylococcus aureus and Klebsiella pneumonia on laundry.

8. Pro-Enzyme Laundry Detergent Powder - Proprietary Active Enzymes for Home Washing Used by

Pro-Enzyme Laundry Detergent Powder - Proprietary Active Enzymes for Home Washing Used by
7.9

Absolute Best Cleaning Products

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  • TRADE-SECRET FORMULATION MADE IN THE USA - Used by professionals for years, but now made available for all home use washing machines.
  • POTENT ACTIVE ENZYME BLEND - Our concentrated powder detergent is formulated with very powerful enzymes that remove and eliminate trapped organic odors from all bodily fluids like sweat from fitness and gym clothes
  • ALL PURPOSE DETERGENT - Brings fabric colors back to life, brighten bedding, and makes whites whiter. Effective in all water types and machines, including High Efficiency washing machines.

9. Puracy Laundry Detergent - Enzyme-Powered Liquid Laundry Detergent Concentrate, Natural Laundry

  • Clean, Fresh Laundry Without Irritating Residues: You can now have clean laundry and reduce waste (less plastic, water, and energy; accurate dosing) using safe, plant-powered ingredients.
  • Created by MDs and PhDs: For Sensitive Skin & Allergy Sufferers. No Sulfates (SLS, SLES, SCS), or Bleach.
  • 99.4% Plant-Powered, 0% Compromise: Use on delicate & dark clothing, microfiber towels, cloth diapers, septic & greywater systems; Never tested on animals; Made in the USA.
  • No Overly Aggressive Chemicals: No phosphates, sulfates, petrochemicals, animal by-products, chlorine, perfumes, gluten, tree nut-based ingredients, dyes, allergens.

10. Rockin' Green 45oz (90 Loads) Active Wear Detergent - All Natural Laundry Detergent Powder - Vegan

Rockin' Green 45oz (90 Loads) Active Wear Detergent - All Natural Laundry Detergent Powder - Vegan
8.5

Rockin' Green

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  • Premium Active Wear Detergent - Wash off tough stains and odors from long workouts with Rockin' Green Active Wear Laundry Detergent Powder. Powerful yet skin-friendly, this all natural laundry detergent not only keeps your active wear in great condition, but it also works great on all types of fabric!
  • Plant-Powered Ingredients - Dermatologist-tested and hypoallergenic, this powder laundry detergent is made with plant-derived ingredients so it's safe even for babies. Unscented and all-natural, it is formulated with plant-based enzymes ideal for delicate clothes and gentle on sensitive skin.
  • Suitable for All Washing Machines - You can also use this activewear laundry detergent as a pre-soak. This 45-oz laundry powder cleans approximately 90 loads! It has a super concentrated formula so you only need 1 tablespoon per load!
  • Cleaner Clothes, Cleaner Planet - Live a cleaner, greener lifestyle with our 100% biodegradable non-toxic laundry detergent. Free of bleach, dyes, parabens, phosphates, phthalates, SLS/SLES, optical brighteners, and artificial fragrances, Rockin' Green cleaning products are vegan and cruelty-free.
  • Rock the Green Lifestyle - We are on a mission to create economical, hardworking and biodegradable cleaning products to meet the demands of every family. Wed love for you to join the Rockin Green movement and enjoy safe and reliable products! If you are not satisfied with your purchase, contact our customer support and we'll get back to you within 48 hours.

Peter

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