Navigating the many Best B Complex For Mthfr options on the market – from major brands like Igennus Healthcare Nutrition,Triquetra Health,Integrative Therapeutics,Pure Therapro Rx,Seeking Health to lesser-known names – can feel overwhelming. But we’re here to help simplify your search for the best products.
After extensive research testing hundreds of Best B Complex For Mthfr, we’ve selected the top contenders. Our number one recommendation is Igennus Healthcare Nutrition Best B Complex For Mthfr based on its stellar performance and quality. Below you’ll find more of our top-rated picks for the best Best B Complex For Mthfr currently available.
Be sure to consult our handy buying guide as well for expert tips on choosing the right Best B Complex For Mthfr to suit your individual needs. It has all the crucial information you need to make an informed purchasing decision. With our guidance backing your choice, finding your perfect match will be smooth sailing!
Editor's Choice
Super B-Complex – Methylated Sustained Release B Complex & Vitamin C, Folate & Methylcobalamin,
Premium Pick
L Methyl Folate 15mg plus Methyl B12 Cofactor - Professional Strength, Active 5-MTHF Form - Supports
Budget Pick
Integrative Therapeutics Active B-Complex - Energy Metabolism Support* - B-Complex Vitamin
Top 10 Best B Complex For Mthfr
We researched and compared the top products in the Best B Complex For Mthfr category to provide you with these recommendations.
1. Super B-Complex – Methylated Sustained Release B Complex & Vitamin C, Folate & Methylcobalamin,
- HIGH STRENGTH, SUPER ABSORBABLE B complex vitamins including thiamine (B1), Riboflavin-5-phosphate (B2), Nicotinamide (flush free Niacin - B3), Calcium D-pantothenate (B5) & D-Biotin (B7)
- METHYLATED VITAMIN FORMS that the body utilises immediately: bioavailable folate as Quatrefolic, Pyridoxal-5-Phosphate (Vit B6), methylcobalamin (Vit B12) - no poorly absorbed cyanocobalamin
- SUSTAINED RELEASE provides all-day nutrient coverage and twice daily dosing optimises B12 levels
- INTENSIVE HEALTH SUPPORT for energy metabolism, the immune and hormonal systems, homocysteine regulation, nutrient metabolism, heart function and psychological function
- PURE & CLEAN: vegan, non-GMO, hypoallergenic ingredients, no unpleasant fillers (silicon dioxide, magnesium stearate or titanium dioxide). Lab verified, GMP manufactured in the USA. Earthy odor due to bioactive vitamin forms
2. L Methyl Folate 15mg plus Methyl B12 Cofactor - Professional Strength, Active 5-MTHF Form - Supports
- PROFESSIONAL STRENGTH: Provides clinically validated dosage of 15mg L Methyl folate in the 5-MTHF calcium salt form. This is the most active form of Folate.
- ESSENTIAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships. Both are crucial in the body's methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.
- ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is immediately absorbed into the bloodstream because it does not require processing or breakdown by the body. This is crucial for those with methylation issues that cannot properly process folic acid.
- BRAIN, MOOD & ENERGY SUPPORT: Essential to neurotransmitters production involved in concentration, sleep, energy, hormones & mood.*
- CARDIOVASCULAR, NITRIC OXIDE & NERVE SUPPORT: Supports heart health and nerve function by supporting healthy homocysteine levels and nitric oxide production.
3. Integrative Therapeutics Active B-Complex - Energy Metabolism Support* - B-Complex Vitamin
- Active B-Complex Supplement: Provides all 8 B-vitamins in a high-potency blend containing active forms of vitamins B2, B6, B12, and folate; includes choline to support healthy brain function*
- Cellular Energy Production: Supports cellular energy production through the metabolism of carbohydrates, proteins, and lipids; converts food into fuel to help you tackle the day*
- Essential B Vitamins: B vitamins play essential roles in supporting cell function, the nervous system, and cellular energy production; supports the synthesis of serotonin, dopamine, and GABA*
- Nervous & Immune System Support: Folate plays an essential role in nervous system and immune system functions*; our supplement is formulated with the Quatrefolic brand L-methylfolate
- Your journey to wellness is easier to navigate with a trusted partner by your side; to find the right products for you, we recommend joining forces with your healthcare provider
4. Pure Therapro Rx Methyl B Complete, Methylated B Complex Vitamins, 120 Capsules, Quatrefolic 5-MTHF
- : Our Methylated B complex vitamins provide essential B vitamins to support methylation processes. Featuring Folate as Quatrefolic for increased bioactivity, TMG Betaine (also known as TMG Trimethylglycine), and Vitamin B12 Methylcobalamin and Adenosylcobalamin, B6, and B2, ours is a super methyl B complex that provides vitamins essential for overall wellbeing, including energy production.
- : We only use patented, clinically studied ingredients. You absolutely won't find any fillers, excipients, flow agents or ingredients sourced from China in these methyl B complex vitamin supplements. Moreover, our Vitamin B Complex Capsules contain absolutely no gluten, wheat, soy, corn, yeast, animal products, nuts, artificial preservatives, sweeteners, or colors. We always promise to put quality first with absolutely no exceptions.
- : Our Methyl Folate supplement support melatonin synthesis. Supplementing with its bioactive form, 5-MTHF, ensures effective folate activation despite enzyme issues.
- : Manufactured in an NSF-certified facility right here in the USA, our third-party tested B vitamins complex follows the FDA's strict cGMP guidelines. Each bottle of our B complex vitamin supplement contains sixty (60) capsules. Each capsule contains 25 mg Riboflavin, 15 mg Vitamin B6, 3,400 mcg Folate, 1,000 mcg Vitamin B12 Methylcobalamin, and 650 mg TMG trimethylglycine.
- : Methyl B12 is packed with essential B vitamins to support healthy methylation and homocysteine levels to support cardiovascular and brain health. With B6, Methylcobalabin B12, Folate, riboflavin and TMG.
5. Seeking Health Active B12 with L-5-MTHF, 60 Lozenges, Vitamin B12 Supplement, Supports Cellular
- HEALTHY ENERGY LEVELS: Active B12 with L-5-MTHF by Seeking Health provides 1,360 mcg DFE (800 mcg) of pure non-racemic L-methylfolate in an easy-to-take lozenge, along with two active coenzyme forms of vitamin B12 to give you the energy you need.*
- HEALTHY MOOD AND FOCUS: Experience a supported healthy mood, focus, energy, and clarity. Note: This is a situational supplement; only take it when you feel that you need it. Other than those times, dont take it, or as directed by your healthcare professional.*
- IDEAL FOR MTHFR GENE MUTATION: By taking this combination of methylated nutrientsmethylfolate and methylcobalaminin Active Vitamin B12 with L-5-MTHF, your methylation pathway is supported and your MTHFR gene mutation symptoms are supported.*
- LOZENGE: This easy-to-take and great-tasting lozenge isnt your typical daily supplement. You should take it on an as-needed basis, or as directed by your healthcare professional. When you have a slight brain fog or feel unfocused, or fatigued, start with a small portion.*
- CONSISTENT QUALITY: At Seeking Health, every ingredient is carefully sourced, researched, and tested. Each meets strict specifications for manufacturing standards before any ingredient is allowed for use. We use only the highest-quality ingredients.
6. Organic Methyl Folate 1000 mcg + Methyl B12 Cofactor (300 Servings) – Metabolically Active 5-MTHF
7. Codeage Methylfolate B Complex Supplements - 5 MTHF, Methylcobalamin 1000mcg Methylated Vitamin B12,
- MTHF supplement: Methylfolate B Complex offers an all-in-one methylation supplement with folate, methylated vitamins, riboflavin, and betaine in an easy to use capsule format.
- Folate & riboflavin: 1360 mcg of 5- MTHF folate with Quatrefolic 5 methylfolate and glucosamine salt as a folate supplement. This methylation formula also contains 30 mg of Riboflavin 5- Phosphate as a riboflavin supplement.
- Betaine: The blend features 600 mg of betaine as trimethylglycine (TMG).
- Methylated vitamins: Codeage Methylfolate B Complex can provide an active, methylated forms of folate and vitamins B2, B6, B12 (5-MTHF and methylcobalamin B12). The vitamins included in this formula (vitamin B6 and vitamin B12 1000 mcg) are also provided in their phosphorylated forms.*
- Vegan, gluten free, non-GMO, & made in USA: Codeage Methylfolate B Complex supplement is vegan, and non-GMO. This formula is also gluten, dairy, and soy free. Codeage methylated vitamins capsules are manufactured in the USA in an cGMP certified facility and third party tested. 2 months supply.
8. 1 Body Vitamin B Complex – Methylated 5-MTHF Folate with B1, B2, B5, B6, Methyl B12, Niacin,
- Super B Complex Vitamins - Get the benefit of a full-spectrum B vitamin complex that includes all B vitamins, including B1, B2, B5, B6, methylcobalamin B12, Niacin, Folate (5-MTHF), and Biotin
- Includes Magnafolate Brand L-Methylfolate - This patented delivery system supports optimal methylation through the MTHFR gene, which converts folic acid into its active form, methylfolate.
- Improved Energy - Great for men, women, and children, B vitamins are scientifically proven to support the metabolism and ATP energy production
- Mood Support & Stress Relief - B vitamins supports nervous system health, stress relief, mood, and overall well-being
- High Quality B Vitamins - Our B vitamin complex uses the highest-quality ingredients and our vitamin B complex capsules are vegan-friendly and manufactured in the USA
9. THORNE Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6, and B12 - Supports
- Healthy Methylation: Methyl-Guard Plus supports methylation and promotes a healthy level of homocysteine
- Active Forms: Formulated with active folate (5-MTHF) and the active, tissue-ready forms of vitamins B2, B6, and B12 to optimize absorption
- Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
- Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams
10. Thorne Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular
- Nervous System: Promotes an optimally functioning nervous system and healthy nerve cells
- Cellular Energy: B vitamins promote cellular energy production by supporting the conversion of carbohydrates into energy, as well as the metabolism of fats and proteins
- Complete Formula: An optimal balance of eight B vitamins, plus choline, in their active form to enhance absorption in the body
- Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
- Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams
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