With so many great Best Systemic Enzymes to pick from, like those from brands such as Pure Encapsulations,MaryRuth Organics,Rootcology,Wonder Laboratories,Doctor’s BEST,VITÄLZYM, it can be tricky for customers to decide what to buy. But after extensive research, we’ve discovered the stand-out Best Systemic Enzymes currently on the market.
Our team rigorously tested numerous products available to consumers. The one that stands at the top of our list is Pure Encapsulations Best Systemic Enzymes, thanks to its impressive performance and features. Below you’ll find more of our top-rated picks, along with insightful analysis from our seasoned experts. Check out their thoughts before making your purchasing choice. With this guide backing your decision, you’re sure to end up with a Best Systemic Enzymes you’ll love.
Editor's Choice
Pure Encapsulations Systemic Enzyme Complex - Supports Muscle Recovery & Joint Health - for Immune
Premium Pick
MaryRuth Organics Serrapeptase Enzymes Capsules | Up to 2 Month Supply | Enzyme Supplement for High
Budget Pick
Rootcology by Dr. Izabella Wentz | Systemic Enzymes | Support Normal Tissue Repair with Turmeric and
Top 10 Best Systemic Enzymes
We researched and compared the top products in the Best Systemic Enzymes category to provide you with these recommendations.
1. Pure Encapsulations Systemic Enzyme Complex - Supports Muscle Recovery & Joint Health - for Immune
- Essential Enzyme Blend: Systemic Enzyme Complex protease enzyme supplement features pancreatin, protease, serrazimes, bromelain, and papain for muscle, joint, and immune health*
- Enzyme Support: Formulated with papaya fruit and other enzymes, this blend offers impressive overall health support, supporting muscle comfort and recovery*
- Joint Health: Formula contains 250 mg of Indian frankincense (Boswellia serrata), a potent boswellia supplement for robust joint support and cartilage health*
- Suggested Use: As a dietary supplement, take 3 digestive enzyme capsules, 1-2 times daily, between meals
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs
2. MaryRuth Organics Serrapeptase Enzymes Capsules | Up to 2 Month Supply | Enzyme Supplement for High
- Serrapeptase Systemic Enzymes: This proprietary blend of enteric-coated Serrapeptase (also known as Serratiopeptidase) and a Protease blend is combined with enzyme-enhancing vitamins and minerals to support your overall health. Encapsulated in pine-based vegan capsules | you can easily incorporate these into your routine.Serrapeptase Systemic Enzymes: This proprietary blend of enteric-coated Serrapeptase (also known as Serratiopeptidase) and a Protease blend is combined with enzyme enhancing vitamins and minerals to support your overall health. Encapsulated in pine-based vegan capsules | you can easily incorporate these into your routine.
- Multiple Benefits: Serrapeptase may help to support the body's circulatory system | healthy tissue homeostasis | and the bodys natural inflammation process. This powerful enzyme blend may support cellular | tissue | and systemic health | while promoting healthy immune activity and aiding your body in maintaining normal microbial balance.
- Advanced Enzyme Complex: 120 000 SPU Serrapeptase in each capsule. Sometimes referred to as a super enzyme, serrapeptase has been shown to affect the movement of immune cells, while the Protease blend works at normal cellular detoxification to efficiently digest all types of proteins. Pairing these enzymes with cofactor vitamins and minerals helps your body use the enzymes faster and more efficiently.
- Easy Efficient Absorption: This supplement is formulated to be taken systemically, not digestively. It's best to take it on an empty stomach, allowing the enzymes to support your body rather than digest your food. Adults take one capsule up to two times daily or as recommended by a physician or healthcare professional. For best results, take it on an empty stomach with a large glass of water 30-60 minutes before or 2 hours after a meal.
- For Most Lifestyles, MaryRuth's Serrapeptase Systemic Enzymes are Non-GMO and Vegan. They are Dairy-Free, Nut-Free, Gluten and Wheat-Free, Soy-Free, Nightshade-Free, and Sugar-Free. This product contains maltodextrin, which is corn-derived.
3. Rootcology by Dr. Izabella Wentz | Systemic Enzymes | Support Normal Tissue Repair with Turmeric and
- Supports Joint and Tissue Health: Formulated with proteolytic enzymes to aid in maintaining healthy joints and support normal tissue repair.*
- Enhances Antioxidant Defense: Provides nutrients that contribute to the body's natural antioxidant mechanisms.*
- Two Capsules Per Day: Rootcology Systemic Enzymes contain a stronger formulation than is used in many other brands, which does not require a large number of capsules. Just two capsules per day is recommended.*
- Clean and Allergen-Friendly Formula: Free of common allergens, suitable for various dietary needs. All Rootcology products are lab tested and use pure formulas.
- Created by a Pharmacist & Thyroid Expert: Dr. Izabella Wentz, Pharm.D., FASCP is a passionate, innovative and solution focused clinical pharmacist well versed in finding and evaluating emerging research to help address her clients' unique challenges. Although trained as a pharmacist, she is an ardent champion for lifestyle interventions, which often help patients more than any medications.
4. Wonder Laboratories Proteolytic Enzymes | Bromelain Papain Pancreatin Trypsin 550 mg Total with
- Nutritionally Supports Your Body's Natural Response to Inflammation, Immune Function, and Supports Digestive and Intestinal Health*
- Contains Bromelain, Lipase, Trypsin, Papain, Pancreatin, Chymotrypsin, Protease, and Amylase
- Bromelain and Proteolytic Enzymes to help support the breakdown of proteins in digestion, immune function, and other vital processes.*
- Amylase Lipase Bromelain Digestive Enzymes Organic Sources to provide you with a well formulated digestive enzyme
- MADE IN USA - Manufactured and packaged in the USA by a family owned and operated company since 1962.
5. Doctor's Best Proteolytic Enzymes, Broad Spectrum Proteolytic Enzyme Formulation, Non-GMO,
- DOCTOR'S BEST PROTEOLYTIC ENZYMES: potent formulation that includes an assortment of veggie proteolytic enzymes. Proteolytic enzymes within the body break down proteins into their constituent amino acids
- IMPROVES DIGESTION: as a natural detox, proteolytic enzymes aid in the proper digestion of carbohydrates, fats, and proteins. Promotes a cleaner and healthier digestive system and aids with indigestion
- HEALTH BEGINS IN YOUR GUT: maintaining a healthy digestive system is essential for overall well-being, and by taking enzymes to support gut health, you can improve your immune system function
- NUTRIENT ABSORPTION: Bromelain, papain, serratiopeptidase, and fungal protease, are absorbed through the lining of digestive tract and into the circulation. Helps break down fats, carbs, and protein more efficiently
- DELAYED RELEASE VEGETARIAN CAPSULES: help active ingredients to get into intestines for proper absorption and function to support overall immune system health
6. VITÄLZYM Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase, Immune and Joint
- Enteric Coated Advanced Supplements: Vitalzym high potency features an advanced enteric coated system designed for maximum absorption into the bloodstream. Unlike powder or tablet-based proteolytic systemic enzymes, our vegetarian soft gels deliver consistent, reliable support.
- Premium Multi-Enzymes: Each serving includes serrapeptase, bromelain, papain, rutin, amylase, protease, lipase, and amla extract, making these serrapeptase capsules a balanced proteolytic enzymes formula in convenient liquid gel capsules.
- Supports Overall Wellness: Formulated to supports overall wellness, this supplement helps in joint support, helps Supporting to dissolve unwanted proteins, and respiratory health and blood circulation. Our Vitalzym combines natural enzymes to complement a balanced lifestyle, healthy diet, and regular activity.
- Easy-to-Swallow Soft gels: Designed for convenience, and our serrapeptase supplement comes in small, easy-to-swallow gel caps with high absorption due to the fact of passing harsh stomach acid. Each capsule contains a potent blend of systemic enzymes for vitality, strength and joint support made with vegetarian ingredients.
- Quality You Can Trust: Made in Japan by a team of international scientists, vitalzym extra strength soft gels are vegetarian, gluten-free, dairy-free, and yeast-free. A thoughtful choice for those seeking capsules for overall wellness with natural proteolytic enzymes.
7. WellnessOne ProOneZyme Digestive Enzymes Supplements - Systemic Proteolytic Enzymes for Digestion,
- Advanced Digestive Support - This powerful blend of digestive and proteolytic enzymes for digestion and gut health helps break down proteins, fats, carbs, gluten, and dairy, supporting nutrient absorption and easing occasional gas, bloating, and post-meal discomfort.
- Potent Enzyme Blend A full-spectrum mix of systemic enzymes including nattokinase, seaprose-S, protease, and bromelain, carefully selected to support a healthy inflammatory response, circulation, and digestive health.
- Joint Comfort & Recovery More than just digestive support, ProOneZyme promotes a healthy inflammatory response. It helps support joint comfort and ease occasional muscle soreness from physical activityideal for post-exercise recovery and daily mobility.
- Potent & Well-Dosed for Results Each bottle includes 90 capsules (30 servings). Take 3 easy-to-swallow capsules daily on an empty stomach or start with 1 capsule with food for 12 weeks, then increase to 23 as tolerated. Recommended for women ages 3065+.
- Made with You in Mind - ProOneZyme is formulated by vitamin experts using high-quality, Non-GMO ingredients. Manufactured in a GMP-certified facility for your peace of mind. We prioritize customer satisfaction, so feel free to reach out if you have any questions!
8. HCP Formulas Fibrenza - Systemic Enzyme Complex with Fibrinolytic & Proteolytic Enzymes - Dietary
- FIBRENZA SUPPLEMENT: An advanced blend of 13 powerful systemic enzymes. HCP Formulas' Fibrenza is a natural systemic enzyme complex. Formulated with fibrinolytic & proteolytic enzymes, Fibrenza supports the body's ability to dissolve fibrin and cleanse the body of impurities for maximum body-wide benefits in a reliable, time-released capsule.
- CARDIOVASCULAR SUPPORT: Aging lowers your body's ability to produce sufficient levels of enzymes, often leading to build-up of fibrin. Fibrenza harnesses potent systemic enzymes that break down proteins, toxins, and other cellular debris, such as Serrapeptase and Nattokinasehelping to maintain a healthy cardiovascular system.
- ANTIOXIDANT: Enzymes possess profound antioxidant properties. These properties are the foundation of anti-aging and detoxification protocols, Superoxide Dismutase helps break down potentially harmful oxygen molecules in cells that help to maintain overall well-being.
- SUPERIOR DELIVERY: Fibrenza utilizes a technologically advanced capsule without phthalates. Unlike enteric coatings, AcidDefenz capsules use a non-GMO vegetable cellulose barrier to provide for a time-release for more consistent enzyme absorption.
- PREMIUM INGREDIENTS: HCP Formulas specializes in ultra-premium nutraceutical supplements to better support your health. We source only the highest-grade Non-GMO ingredients that are vegetarian and free of gluten, dairy, wheat, yeast, and shellfish. Fibrenza contains NO Phthalates, Talc, or artificial colors or flavors and is proudly manufactured in the USA in GMP registered facilities.
9. Arthur Andrew Medical, Neprinol AFD, Multi Enzyme Blend with Serrapeptase & Nattokinase, 90 Count
- Whole body enzyme support: Support immune health, joint comfort, circulation, and digestion with our proprietary enzyme blend including high doses of nattokinase & serrapeptase*
- Advanced fibrin defense: A powerful enzyme blend with serrapeptase, nattokinase and lipase (30,000 FU/serving) breaks down the excess fibrin in your bloodstream
- Blood cleansing action: Clears the blood of unwanted proteins that can irritate the immune system;* Supports tissue repair and promotes a healthy inflammatory response to everyday activity*
- Two to three servings daily: Take with water, on an empty stomach; Vegan, non-GMO and kosher certified; Our chemical-free Acid Armor capsules are designed to resist stomach acids, ensuring superior absorption
- Innovation and science: Unlock your health's true potential with our therapeutic-grade enzyme and probiotic products, thoroughly tested for superior quality and purity
10. Medizym Naturally Vitamins, Systemic Enzyme, Support for Healthy Inflammation Response, Immune
- Naturally Vitamins
Peter
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