Best Spider Poison

Peter | 06-01-2026

With so many great Best Spider Poison to pick from, like those from brands such as Ortho,Terro,Wet & Forget,HOT SHOT,MGK, it can be tricky for customers to decide what to buy. But after extensive research, we’ve discovered the stand-out Best Spider Poison currently on the market.

Our team rigorously tested numerous products available to consumers. The one that stands at the top of our list is Ortho Best Spider Poison, thanks to its impressive performance and features. Below you’ll find more of our top-rated picks, along with insightful analysis from our seasoned experts. Check out their thoughts before making your purchasing choice. With this guide backing your decision, you’re sure to end up with a Best Spider Poison you’ll love.

Editor's Choice
Onslaught Fastcap Spider Scorpion Insecticide Kills Scorpions Spiders Mks 32 Gls
Onslaught Fastcap Spider Scorpion Insecticide Kills Scorpions Spiders Mks 32 Gls
Premium Pick
Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2, Controls Ants, Roaches, Spiders
Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2, Controls Ants, Roaches, Spiders
Budget Pick
Wet & Forget 803064 Miss Muffet's Revenge Indoor and Outdoor Spider Killer with Attached Sprayer, 64
Wet & Forget 803064 Miss Muffet's Revenge Indoor and Outdoor Spider Killer with Attached Sprayer, 64

Top 9 Best Spider Poison

We researched and compared the top products in the Best Spider Poison category to provide you with these recommendations.

1. Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand, Controls Ants,

  • Ortho Home Defense Insect Killer for Indoor & Perimeter2 kills the toughest home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish and periodical cicadas (as listed)
  • This insect killer spray provides a long-lasting bug barrier of up to 12 month protection against ants, roaches and spiders indoors on non-porous surfaces
  • Use this pest control spray indoors in kitchens and bathrooms or around doors and windows, and outdoors to the perimeter of foundations, patios, decks, garages or wherever insects are a recurring problem
  • Apply this bug killer anytime as a preventative treatment or after you see evidence of insect activity
  • This 1.33 gal. container of Ortho Home Defense Insect Killer for Indoor & Perimeter2 comes with a battery-powered Comfort Wand, which delivers a continuous spray for easy application

2. TERRO T2302 Spider, Ant, Roach, and Other Insects Killer Aerosol Spray – 2 Pack

  • 2 spray bottles
  • Kills spiders (including Black widow, brown recluse and hobo spiders), ants, cockroaches, crickets, scorpions, and other insects
  • Kills on contact
  • Can be used indoors and outdoors

3. Wet & Forget 803064 Miss Muffet's Revenge Indoor and Outdoor Spider Killer with Attached Sprayer, 64

Wet & Forget 803064 Miss Muffet's Revenge Indoor and Outdoor Spider Killer with Attached Sprayer, 64
8.9

Wet & Forget

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  • Kills spiders and creates a barrier inside and outside the home to keep them away for up to 12 months with just one application
  • Attached sprayer for quick and easy application with a spray range of up to 10 feet for those hard to reach places
  • Treat all areas were spiders are found, spray until wet but not soaking and for long lasting results leave spray undisturbed
  • Apply in calm weather where rain is not expected for 24hrs and allow to dry completely before entering treated area
  • Miss Muffet's Revenge is ready to use and specially formulated for all spiders except Black Widow and Brown Recluse

4. Hot Shot Spider & Scorpion Killer (Aerosol), Kills Large Spiders and Scorpions in Seconds, Including

Hot Shot Spider & Scorpion Killer (Aerosol), Kills Large Spiders and Scorpions in Seconds, Including
8.5

Hot Shot

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  • KILLS IN SECONDS: The fast-acting formula kills spiders, scorpions and other listed insects in seconds
  • KILLS FOR UP TO 4 MONTHS: Keeps killing ants (excluding harvester, pharaoh and fire ants), cockroaches and crickets for up to 4 months
  • KILLS BLACK WIDOW SPIDERS: Also kills black widow spiders as they hatch
  • UP TO 5-FT TARGETED SPRAY: Broad spray pattern ensures full coverage of treatment area
  • NO-MESS FORMULA: The water-based formula is non-staining and leaves no oily residue or lingering odor

5. Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand, Kills Ants, Roaches,

  • Start killing ants, roaches, spiders, fleas and ticks with Ortho Home Defense Max Indoor Insect Barrier
  • This insect control spray kills listed bugs and protects your home for 365 days against ants, roaches and spiders indoors on nonporous surfaces
  • Use this indoor insect spray in kitchens, bathrooms and basements, and around doors and windows; apply outdoors to foundations to create a barrier around your home
  • Create an insect barrier anytime as a preventative treatment or after you see evidence of insect activity
  • Apply Ortho Home Defense Max Indoor Insect Barrier using the Extended Reach Comfort Wand, which lets you spray without bending

6. Onslaught Fastcap Spider Scorpion Insecticide Kills Scorpions Spiders Mks 32 Gls

7. MGK Onslaught® FastCap Spider and Scorpion Insecticide | Indoor/Outdoor Concentrate | Commercial

  • CONVENIENT PEST CONTROL: Protection against a wide range of residential and commercial pests populations including spiders, scorpions, fleas and mosquitoes.
  • QUICK KILL: Onslaught FastCap Spider and Scorpion Insecticide offers a convenient and approach to pest control.
  • INDOOR AND OUTDOOR APPLICATIONS: Effective pest control in and around livestock facilities, on turf, ornamentals, landscapes, and in food and non-food areas of commercial and residential structures.
  • ACTIVE INGREDIENTS: Combines esfenvalerate and prallethrin with synergist piperonyl butoxide (PBO) for fast-acting pest control.
  • A LEGACY YOU CAN TRUST: Driven by expertise and industry commitment, MGK has been developing pest control products based primarily on botanical and innovative technologies since 1902.

8. TERRO Scorpion Killer Spray - Kills Scorpions, Spiders, Ants, Roaches, and More - T2102-6 - Ready to

  • KILL SCORPIONS & MORE: TERRO Scorpion Killer Spray kills scorpions, spiders, ants, roaches, crickets, and other insects
  • IMMEDIATE RESULTS: Kills on contact and provides residual control for up to 6 weeks
  • VERSATILE TREATMENT OPTIONS: The nozzle's two-way spray is ideal for spot application or crack-and-crevice treatment
  • INDOOR AND OUTDOOR TREATMENT: TERRO Scorpion Spray can be used indoors and outdoors
  • 16 FL OZ CAN: Comes in a 16 oz aerosol spray can

9. Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2, Controls Ants, Roaches, Spiders

  • Ortho Home Defense Insect Killer for Indoor & Perimeter Refill2 kills the toughest home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish and periodical cicadas (as listed)
  • This insect killer spray provides a long-lasting bug barrier of up to 12 month protection against ants, roaches and spiders indoors on non-porous surfaces
  • Use this pest control spray indoors in kitchens and bathrooms or around doors and windows, and outdoors to the perimeter of foundations, patios, decks, garages or wherever insects are a recurring problem
  • Apply this bug killer anytime as a preventative treatment or after you see evidence of insect activity
  • This 1 gal. Ortho Home Defense Insect Killer for Indoor & Perimeter Refill2 allows you to reuse your Comfort Wand from its original container

Peter

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