Best Serotonin Supplements Reviews

Peter | 06-01-2026

You will find our hand-picked selection of Best Serotonin Supplements Reviews below. You have a wide variety of choices of brands such as TWINLEAF,NATURAL STACKS,Double Wood Supplements,Dr. Maxwell,DR. EMIL NUTRITION available to you as a result of the fact that each one of them has a unique pricing, look, and feel. Continue reading for an in-depth analysis in our Best Serotonin Supplements Reviews buying guide!

Our experts tested a variety of Best Serotonin Supplements Reviews on the market. Right at the top of the list is TWINLEAF Best Serotonin Supplements Reviews. Check out some more of our favorites below, and read some valuable insight from our experienced editors.

Editor's Choice
Natural Serotonin Supplement - Made in USA Manganese Serotonin & Cortisol Manager - Serotonin
Natural Serotonin Supplement - Made in USA Manganese Serotonin & Cortisol Manager - Serotonin
Premium Pick
Serotonin Brain Food - 1250mg L-Tryptophan & 400mg Rhodiola Rosea Supplement - Mood Support
Serotonin Brain Food - 1250mg L-Tryptophan & 400mg Rhodiola Rosea Supplement - Mood Support
Budget Pick
5HTP Liquid Drops - More Absorbable and Effective Than 5 HTP Capsules (60 Servings of 50mg 99%+
5HTP Liquid Drops - More Absorbable and Effective Than 5 HTP Capsules (60 Servings of 50mg 99%+

Top 10 Best Serotonin Supplements Reviews

We researched and compared the top products in the Best Serotonin Supplements Reviews category to provide you with these recommendations.

1. Natural Serotonin Supplement - Made in USA Manganese Serotonin & Cortisol Manager - Serotonin

Natural Serotonin Supplement - Made in USA Manganese Serotonin & Cortisol Manager - Serotonin
9.8

Twinleaf

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  • Serotonin Supplement for Overall Health - boost your health with Twinleaf Serotonin Booster! This natural serotonin supplement for women and men is filled with L-tryptophan, 5-HTP, GABA, and B vitamins - ingredients that help you produce and absorb your serotonin. Serotonin supports your overall health, well-being, and energy levels, so it's a great source of wellness!
  • Serotonin & Cortisol Manager - Twinleaf serotonin supplement promotes healthy and balanced well-being. It also includes potent ingredients like vitamins B6 and B12, 5-HTP, and GABA, which help manage your daily serotonin and cortisol levels. L-theanine and L-tryptophan will also provide healthy and stable energy throughout your day. Stay productive and energized!
  • Serotonin Booster with 5-HTP - Our serotonin supplement contains vitamins, essential serotonin precursor nutrients, amino acids, and botanical extract blend with Gotu Kola, Bacopa Monnieri, Passionflower, and St. John's Wort. With this professional-grade formula, all ingredients work together to ensure their proper absorption and overall multi-directional positive effect.
  • Positive Experience Guarantee - Your satisfaction with Twinleaf products is our highest priority. If something is wrong with your purchase, write to us directly, and well do our best to make things right for you and improve your experience. We are always ready to hear your questions, opinions, and suggestions at any time.

2. Serotonin Brain Food - 1250mg L-Tryptophan & 400mg Rhodiola Rosea Supplement - Mood Support

Serotonin Brain Food - 1250mg L-Tryptophan & 400mg Rhodiola Rosea Supplement - Mood Support
9.5

Natural Stacks

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  • Powerful Serotonin Support Formula Designed to support serotonin production already within healthy, normal levels. This formula combines key amino acids and essential cofactors to support a positive mood, emotional well-being, and a sense of relaxation while supporting stress response and irritability.*
  • L-Tryptophan for Serotonin Production & Mood Support Each serving delivers 1250mg of L-Tryptophan, an essential amino acid that serves as a direct precursor to serotonin. Unlike 5-HTP, which skips a key regulatory step in serotonin metabolism, L-Tryptophan follows the bodys natural pathway, allowing for proper serotonin synthesis and utilization.*
  • 400mg Rhodiola Rosea for Stress Support This adaptogenic herb helps the body adapt to stress while supporting serotonin function. It promotes emotional stability, mental focus, and a calm, uplifted state to help you stay clear-headed throughout the day.*
  • Magnesium & B-Vitamins for Optimal Neurotransmitter Function Essential cofactors like Magnesium Glycinate, Vitamin B6, and Zinc work together to support serotonin synthesis, aid relaxation, and support overall brain function for a more positive mood and restful sleep.*
  • Backed by Open-Source Transparency Natural Stacks is committed to ingredient traceability, 3rd-party lab testing, and 100% label disclosure, ensuring you know exactly what you're putting in your body.*

3. 5HTP Liquid Drops - More Absorbable and Effective Than 5 HTP Capsules (60 Servings of 50mg 99%+

5HTP Liquid Drops - More Absorbable and Effective Than 5 HTP Capsules (60 Servings of 50mg 99%+
9.1

Double Wood Supplements

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  • FEEL THE DIFFERENCE: Effects of our 5 HTP drops even at the 50mg dose may be far more noticeable than encapsulated 5 HTP products
  • SEROTONIN SUPPLEMENT: 5 HTP is an amino acid that is converted into serotonin in the brain. This may help support mood and Nighttime
  • UNIQUE 5-HTP DROPS: Double Wood offers the first ever maximum absorption 5 HTP drops that are over 99% 5-HTP. Check the supplement fact panel of other 5 HTP supplements, many only offer a 10% product.
  • TWO MONTH SUPPLY: Double Wood offers 60 servings of our 5 HTP supplement per bottle in a convenient dropped format
  • USA PROUD: Our 5 HTP drops capsules are Manufactured in the USA from Globally Sourced Ingredients, Gluten Free, and are Non-GMO

4. Dr. Maxwell Serotonin and Dopamine Supplements, Better Than Dopamine or Serotonin Support Only.

Dr. Maxwell Serotonin and Dopamine Supplements, Better Than Dopamine or Serotonin Support Only.
9.1

Dr. Maxwell

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  • Taking a serotonin and dopamine support supplement is better than taking a supplement to support only dopamine or only serotonin. This is because Dopamine (motivation and reward) and Serotonin (learning and mood) work in a delicate balance. Unlike leading alternatives, Dr Maxwells formula contains precursors of both dopamine and serotonin so it helps maintain normal neurotransmitter levels*
  • Mood support and relaxation: Dr Maxwells formula provides Magnesium and Vitamin D3 to support overall well-being, mood and relaxation*
  • Focus and brain support: our formula contains Ashwagandha, L-theanine and Taurine to support daily cognitive function and mental tasks*
  • Great formula and value. Dr Maxwells 4-in-1 formula provides 1) dopamine precursors, 2) serotonin precursors, 3) nutrients for mood support & relaxation and 4) focus & brain support. If bought separately, these would cost between 60 and 110$*
  • High quality, made from non-GMO, pure ingredients in a GMP and FDA-registered facility. Free from eggs, wheat, peanuts, sweeteners, shellfish and sugar. Please check the DO NOT USE section on the product label, which can be found among the product pictures*

5. Serotonin Brain Food - 1250mg L-Tryptophan & 400mg Rhodiola Rosea Supplement - Mood Support

Serotonin Brain Food - 1250mg L-Tryptophan & 400mg Rhodiola Rosea Supplement - Mood Support
8.7

Natural Stacks

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  • Powerful Serotonin Support Formula Designed to support serotonin production already within healthy, normal levels. This formula combines key amino acids and essential cofactors to support a positive mood, emotional well-being, and a sense of relaxation while supporting stress response and irritability.*
  • L-Tryptophan for Serotonin Production & Mood Support Each serving delivers 1250mg of L-Tryptophan, an essential amino acid that serves as a direct precursor to serotonin. Unlike 5-HTP, which skips a key regulatory step in serotonin metabolism, L-Tryptophan follows the bodys natural pathway, allowing for proper serotonin synthesis and utilization.*
  • 400mg Rhodiola Rosea for Stress Support This adaptogenic herb helps the body adapt to stress while supporting serotonin function. It promotes emotional stability, mental focus, and a calm, uplifted state to help you stay clear-headed throughout the day.*
  • Magnesium & B-Vitamins for Optimal Neurotransmitter Function Essential cofactors like Magnesium Glycinate, Vitamin B6, and Zinc work together to support serotonin synthesis, aid relaxation, and support overall brain function for a more positive mood and restful sleep.*
  • Backed by Open-Source Transparency Natural Stacks is committed to ingredient traceability, 3rd-party lab testing, and 100% label disclosure, ensuring you know exactly what you're putting in your body.*

6. DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e to Maintain Normal Healthy Sleep and Create a Sense

DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e to Maintain Normal Healthy Sleep and Create a Sense
8.5

Dr. Emil Nutrition

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  • Can Support Mood & Rest: We supplemented 200mg of pure 5-HTP with 20mg of SAMe to optimize 5-HTP conversion and support stress levels in the body.*
  • Vitamin B6 for Improved 5-HTP Conversion: Vitamin B6 has been shown to aid 5-HTP conversion. Even a slight B6 deficiency can greatly inhibit the efficacy of 5-HTP.
  • May Promote Calm and Relaxation: Dr. Emils 200 MG 5-HTP Plus formula is a natural way to promote a calm and relaxed mood by supporting 5-HTP conversion in the body.*
  • Doctor-Derived Formula: Dr. Emil Hodzovic has painstakingly formulated our 200 MG 5-HTP Plus supplement with the highest quality ingredients that are gluten-free, non-GMO, and manufactured in a cGMP facility to ensures that each product is 100% free of hype, hormones, and empty promises.
  • Your satisfaction is our priority. All Dr. Emil Nutrition products are completely guaranteed for a full 90 days from the date of purchase.

7. Clean Nutraceuticals GABA 750mg 5 HTP 200mg L Tryptophan 500mg L Theanine 200mg Ashwagandha SAM-e

Clean Nutraceuticals GABA 750mg 5 HTP 200mg L Tryptophan 500mg L Theanine 200mg Ashwagandha SAM-e
8

Clean Nutraceuticals

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  • Advanced GABA Supplements For Women and Men - Our product takes a GABA L-Theanine Supplement and Ashwagandha Supplements and combines them in powder form with L-Tryptophan 500mg and a 5-HTP 200mg and the results are amazing. Normal L Theanine Supplement contain smaller dosages like l theanine 100mg and l theanine 150 mg. However, Clean Nutra has officially created an even more potent all in one supplement.
  • The All In One 5 HTP Supplement You've Been Looking For - Clean Nutra CalmAgain provides multiple full-dose products in one Support & Balance Support complex containing a full L-Theanine and GABA Supplement in a convenient dose. Finally a bigger supplement than GABA , L-Theanine, and 5 HTP have been packed into one convenient solution.
  • Introducing the CalmAgain All In One Supplement - In addition to containing large milligram dosages of L-Theanine 200mg and many 5 HTP Supplements, our formula also contains a whopping of GABA Powder. This is a powerful alternative to GABA, L Theanine, Ashwagandha, and less potent Ashwagandha Capsules. Not your average L-Theanine Supplements, Ashwagandha Pills, and 5-HTP Powder.
  • A Powerful 5-HTP Supplement with Theanine Capsules - CalmAgain is overflowing with potent htp 5 powder, tryptophan capsules, l-theanine, SAMe, L-Glycine, Vitamin D3, Vitamin B6, Magnesium Glycinate, and L Tyrosine. Clear out the countless l theanine drops, 5 htp gummies, tryptophan drops, and aswagandha gummies that are lesser and choose just one inclusive supplement from Clean Nutraceuticals.
  • Vetted and Trusted Ingredients - We pride ourselves in offering a quality supplement that combines the benefits of L- Theanine, ashwagandha extra strength, 5 htp high potency, L Glycine, and Black Pepper Extract. Our formulas are proudly made in a registered and certified facility. Many products offer only a few ingredients like l-theanine 200mg, l theanine 500mg, and l-theanine 400mg. Enjoy an all-in-one Clean Nutra supplement.

8. Quality of Life Pure Balance Serotonin Premium–Helps Boost Serotonin & Cortisol Levels - Includes

Quality of Life Pure Balance Serotonin Premium–Helps Boost Serotonin & Cortisol Levels - Includes
8

Quality Of Life

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  • SUPPORTS MOOD: Our PureBalance Serotonin supplement is made with natural mood enhancing herbs to help reduce stress, support weight management, promote relaxation, and support a positive mood, and help you get more restful sleep.
  • BALANCES SEROTONIN AND CORTISOL LEVELS: PureBalance Serotonin provides the raw material your body needs to make serotonin to bring you one step closer to a healthier you.
  • FROM NATURALLY SOURCED INGREDIENTS: Our formula is made with a proprietary blend of 5-HTP, Venetron and Sensoril helps to boost the effects of our natural stress support.
  • MADE IN THE UNITED STATES: All Quality of Life supplements are manufactured in the USA with globally sourced ingredients in an FDA registered and NSF certified facility that adheres to Good Manufacturing Practices (GMP) to ensure the highest quality of production. Our vegetarian formulated capsules are vegan, gluten free, dairy free, and preservative free.

9. Jarrow Formulas® 5-HTP, 100 mg, Serotonin Precursor, 60 Veggie Capsules, 60 Day Supply

Jarrow Formulas® 5-HTP, 100 mg, Serotonin Precursor, 60 Veggie Capsules, 60 Day Supply
7.9

Jarrow Formulas

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  • Melatonin Production - 5-HTP (5-hydroxytryptophan) is the direct metabolic precursor to serotonin and is important for the production of melatonin, a hormone that aids biorhythm regulation.*
  • Serotonin Synthesis - 5-HTP is an extract of griffonia simplicifolia seeds from West Africa. The formula supports serotonin synthesis.
  • Veggie Caps - Adults take one capsule per day on an empty stomach or as directed by your qualified healthcare professional
  • Superior Science, Smarter Formulas - Informed by strong scientific research, Jarrow Formulas products are carefully crafted to ensure you get the benefit of each and every vitamin, mineral and supplement.
  • Please see this case to completion and confirm that the changes will be maintained. Thank you for your help!

10. BRAINMD Dr Amen Serotonin Mood Support - 120 Capsules - Supports Healthy Serotonin Balance - Gluten

BRAINMD Dr Amen Serotonin Mood Support - 120 Capsules - Supports Healthy Serotonin Balance - Gluten
7.7

Brainmd

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  • BE HAPPY & POSITIVE - Our capsules are formulated to support serotonin balance and production, a natural brain chemical and regulator.
  • CLEAR MIND, MORE ENERGY - Often considered the happy neurotransmitter, serotonin also helps to naturally soothe us and promote a tranquil state. Serotonin is even involved in facilitating deep and lasting rest.
  • APPETITE CONTROL - Serotonin helps control appetite. It also works to minimize the emotional overeating often linked to sadness and the blues.
  • INGREDIENTS - Our pills contain a patented extract of saffron; 5-HTP, a metabolite that converts to serotonin as needed; plus Vitamins B12, B6, and Folate, which are important to the creation of serotonin.
  • QUALITY & PURITY - All BrainMD products are doctor formulated and manufactured in FDA registered facilities. All of our ingredients adhere to strict purity guidelines.

Peter

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