Looking for some of the best Best Pain Numbing Cream? As you may know, there are dozens of brands available in the market such as HealthWise,Subleef,WELMATE,Aspercreme,Tylenol,Ebanel and some come with vastly different price tags. Let us help you out here – we have handpicked the Best Pain Numbing Cream for you.
To compile our list, we’ve researched and evaluated a range of the best-selling products on the market. We recommend HealthWise Best Pain Numbing Cream as our top pick because of its exceptional overall performance. Want to explore more options? Read on! There’s also a buying guide to help you make a wise shopping decision.
Editor's Choice
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical
Premium Pick
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with
Budget Pick
HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10%
Top 10 Best Pain Numbing Cream
We researched and compared the top products in the Best Pain Numbing Cream category to provide you with these recommendations.
1. HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy
- MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
- FAST-ACTING LIDOCAINE Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
- NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
- SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
- Compare to Aspercreme with Lidocaine active ingredients
- 2.7 oz. bottle (49.6g)
2. Subleef Deep Numbing Cream Maximum Strength, Long Lasting Topical Anaesthetic Cream Relief Pain
- Maximum Strength Active Ingredient: Our topical numbing cream is formulated with the highest non-prescription active ingredient percentage available . It penetrates deep to block nerve signals, providing powerful and effective relief from pain, itching, and burning sensations
- Gentle & Fast-Acting Formula: Our cream is carefully crafted to be effective yet gentle on the skin. It absorbs quickly to start working where you need it most, providing a soothing barrier that minimizes procedural discomfort.
- GMP Certified Manufacturing: Every batch is produced under strict Good Manufacturing Practice (GMP) guidelines. This certification is your assurance of a product that meets the highest possible standards for safety, consistency, and quality, trusted by professionals and enthusiasts alike
- Versatile Pain Relief Cream: This cream is a must-have for anyone undergoing cosmetic or personal care procedures for relief from minor skin irritations, burns, or insect bites . It's trusted by anyone with sensitive skin
- We are so confident in the power of our numbing cream that we offer a risk-free guarantee if you are among the extremely rare few who do not achieve the desired deep numbing effect.
3. WELMATE 5% Lidocaine Cream for Hemorrhoids, 6 oz Jar – Fast-Acting Lidocaine Numbing Cream &
- Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
- Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
- External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
- How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
- Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.
4. Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with
- Contains one (1) 4.3-oz. tube of Aspercreme Pain Relief Cream With Max-Strength Lidocaine and Moisturizing Aloe
- Fast-Acting Relief: Experience rapid and lasting pain relief with max-strength 4% lidocaine topical numbing cream, designed to target nerves and numb away pain
- Non-greasy Formula: Fragrance-free Aspercreme moisturizes and relieves without greasy residue or strong odor
- Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible
- Travel-Size: Take your pain relief solution on the go in a compact and portable tube
- Aspercreme is the topical lidocaine brand in the U.S.
5. Tylenol Precise Cooling Numbing Cream, Maximum Strength 4% Lidocaine & 1% Menthol Topical Analgesic,
- Maximum strength numbing relief: 4% lidocaine numbing cream with 1% menthol penetrates to block pain signals at the source; fast-acting cool sensation in under 5 minutes; topical analgesic cream is non-greasy, non-sticky and leaves no residue.
- Roll-on pain relief applicator: Innovative massaging rollerball offers precise, mess-free application for back pain relief products and targeted relief on joints, muscles, knees, shoulders and ankles; portable and easy to use on the go.
- Cooling sensation formula: Fast-acting menthol delivers instant cool relief to soothe minor joint, muscle and arthritis pain; light scent enhances comfort; cream absorbs quickly without greasiness or stickiness for clean, continuous relief.
- Targeted muscle and joint relief: Penetrating formula designed for back, shoulder, hip, knee and elbow pain penetrates deeply to numb minor aches; reapply up to four times daily as directed for sustained comfort throughout the day.
- Non-greasy, fast-absorbing formula: Topical analgesic cream is non-greasy, non-sticky and fast-absorbing for a clean feel; apply a thin layer no more than 34 times daily; ideal pain relief roll on for everyday aches and soreness on the go.
6. Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical
- FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
- 5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
- Enhanced Liposomal Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
- Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
- Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing
7. HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10%
- MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
- PAIN RELIEVING LIDOCAINE + BENZYL ALCOHOL Powerful pain relief ingredients: 4% lidocaine plus 10% benzyl alcohol work together by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
- NON-GREASY FORMULA Non-greasy formula goes on smooth; safely apply 3-4 times daily
- 30-APPLICATIONS PER TUBE Only a dime size of cream is needed per application to targeted areas for up to 30 applications in each tube
- SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
- Compare to Salonpas Lidocaine Plus Pain Relieving Cream active ingredients
- 3.0 oz. tube (85g)
- Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
- Always read detailed instructions before use
8. Adellina Numbing Cream Maximum Strength: Long Lasting Extra Soothing with Arnica and Emu Oil 2OZ/
- Maximum Strength Formula X5 Numbing- Designed to provide a soothing, cooling sensation on contact for enhanced comfort.
- Infused with Natural Botanicals - Contains Arnica and Emu Oil, Known for their skin conditioning and calming properties.
- Cooling and Fast-Absorbing - Lightweight, non-greasy formula that absorbs quickly for temporary comfort.
- Lightweight & Non-Irritating: Odor-free, oil-free formula glides on smoothly without greasy residue or harsh chemicals for mess-free application.
- Made in a GMP-Certified Facility - Quality assured and crafted with skin-friendly ingredients.
9. HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy |
- MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
- FAST-ACTING LIDOCAINE Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
- NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
- SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
- Compare to Aspercreme with Lidocaine active ingredients
- 1.75 oz. bottle (49.6g)
- Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
- Always read detailed instructions before use
10. 5% Lidocaine Topical Numbing Cream: Maximum Strength Topical Anesthetic Numb Cream for Pain Relief,
- 5% Lidocaine Cream Maximum Strength Formula: Formulated with 5% lidocaine, this topical cream provides temporary relief from localized discomfort such as itching, burning, or minor skin irritation. A powerful solution for external use when your skin needs extra care.
- Fast-Acting and Long-Lasting: This lidocaine cream begins to work within minutes, numbing effect begins in 10 minutes, and peak effect in 45-60 minutes. Effects can last for hours, offering extended comfort throughout your daily routine. Numbing performance may vary depending on skin type and treatment area.
- Enriched with Soothing Ingredients: Infused with Vitamin E, Emu Oil, and Allantoin, this formula supports skin hydration and comfort while helping to calm sensitive or stressed areas.
- Fast-Absorbing, Non-Greasy & Gentle on Skin: This lightweight, water-based cream absorbs quickly into the skin, leaving no oily residue behind. Fragrance-free and suitable for sensitive skin types, its designed for easy, mess-free application and everyday comfort.
- Secure, Child-Resistant Packaging: Packaged with a tamper-evident, child-resistant safety cap to reduce accidental access. Easy to carry and store for use whenever temporary relief is needed.
Peter
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