With so many Best Over The Counter Lidocaine Cream brands on the market – from prominent names like Aspercreme,Ebanel Laboratories,WELMATE,HealthWise,Nervive,AneCream to smaller manufacturers – making the right choice can feel overwhelming. But we’re here to help simplify your search for the best product.
We extensively tested and evaluated dozens of top-rated Best Over The Counter Lidocaine Cream across various price points, spending over 100 hours comparing the contenders side-by-side. Based on our in-depth first-hand research, we compiled this list of stand-out Best Over The Counter Lidocaine Cream to consider. Our top recommendation is Aspercreme Best Over The Counter Lidocaine Cream for its uncompromising quality and performance.
Below you’ll discover more of our favorite Best Over The Counter Lidocaine Cream picks. And be sure to consult our buying guide for expert insights on selecting the ideal product for your individual needs and budget. With us guiding your decision, you can shop confidently knowing you’ve chosen an exceptional Best Over The Counter Lidocaine Cream you’ll truly love.



Top 10 Best Over The Counter Lidocaine Cream
We researched and compared the top products in the Best Over The Counter Lidocaine Cream category to provide you with these recommendations.
1. Aspercreme with Lidocaine Maximum Strength Pain Relief Cream, 4.3 Oz

- INCLUDES: One (1) 4.3-ounce bottle of Aspercreme with Lidocaine Maximum Strength Pain Relief Cream
- Relieves Pain at the Source: Topical numbing creme with 4% lidocaine targets more pain receptors to numb away minor pains with no irritation or burning Among counterirritant topical pain relievers
- Works in Minutes: Fast-acting Lidocaine creme penetrates muscles and joints to provide numbing relief for hours
2. Ebanel 5% Lidocaine Topical Numbing Cream Maximum Strength 1.35 Oz, Numb520 Pain Relief Cream

- 5% TOPICAL LIDOCAINE CREAM MAXIMUM STRENGTH - This numbing gel cream temporarily relieves pain, itching, soreness, burning, reduces swelling, and protects irritated skin
- FAST-ACTING & LONG-LASTING - This lidocaine gel cream begins numbing in 3-5 minutes; peaks after 20-25 minutes; lasts for 1 hour from its peak. Enhanced with Liposomal Technology
- EXTRA SOOTHING & HYDRATING FEATURES - Infused with Aloe Vera and Vitamin E, this topical anesthetic numb cream soothes and protects the skin from irritations. Best for minor cuts, minor scrapes, minor burns, insect bites, anorectal disorders
- ODOR-FREE, OIL-FREE & NON-GREASY - Doctor recommended. Water-based skin numbing cream for easy application and no-mess removal
- MADE IN USA - Secured with Child-Resistant Cap, never tested on animals - Cruelty-Free, cGMP Certified, Hypoallergenic, no harsh chemicals, non-addictive. A performance test prior to treatment is highly recommended to assess your best performance timing
3. WELMATE - 5% Lidocaine Numbing Cream, 6oz (170g) - Maximum Strength Lidocaine Cream - Hemorrhoid

- Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
- Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
- External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
- How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
- Made in the USA with globally sourced ingredients.
4. HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy |

- MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
- FAST-ACTING LIDOCAINE Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
- NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
- SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
- Compare to Aspercreme with Lidocaine active ingredients
- 1.75 oz. bottle (49.6g)
- Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
- Always read detailed instructions before use
5. Nervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and

- EXPERIENCE POWERFUL PAIN RELIEF WITH NERVIVE, FROM THE MAKERS OF THE WORLD'S #1 NERVE CARE BRAND: Developed with over 50 years of global nerve care expertise and experience
- BLOCKS NERVE PAIN SIGNALS: Specifically formulated to provide relief directly to areas of pain including toes, feet, fingers, hands, legs, and arms
- WORKS WITHIN MINUTES: Feel the cream start working in minutes for fast-acting, powerful pain relief
- MAXIMUM STRENGTH RELIEF: Maximum levels of Lidocaine HCL 4% and Menthol 1% work within minutes to penetrate nerves and block nerve pain signals
- SOOTHING, NON-GREASY PAIN RELIEVING CREAM: Non-greasy formula that you can massage into areas of pain with ease for soothing relief
- FEEL THE DIFFERENCE WITH NERVIVE
6. AneCream 4% Lidocaine Cream - Topical Lidocaine Numbing Cream - Over-The-Counter Topical Numbing

- FAST ACTING 4% LIDOCAINE CREAM AneCream is a non-greasy over-the-counter topical lidocaine cream specially formulated with soothing agents. Designed for anesthetic use on normal intact skin to relieve itching and minor cuts and scrapes, its provides relief that lasts for ~ 60 minutes.
- OTC PAIN RELIEF CREAM It is your essential OTC pain reliever, perfect for every household's first-aid kit. Keep it within reach whether you're on a cruise ship, in your apartment, dorm room, or even on the road with a first aid kit for your car, it is a must-have in your essentials. It is ideal for travel kits and mini purse essentials, ensuring you're always prepared.
- COOLING Feel the instant cooling effect of AneCream topical numbing cream, whether its a bug bite or a long day in the sun, AneCream is known to have a calming effect on the skin that helps reduce itchiness and inflammation.
- ANTI-ITCHING Don't let bug bites ruin your day. AneCream, fortified with 4 % Lidocaine, offers fast-acting calming relief, ensuring you can enjoy your time outdoors without discomfort.
- CHILD-PROOF AneCream 4% lidocaine numbing cream comes equipped with a child-proof lid. No worries about the kiddos getting into any shenanigans because the child-resistant cap keeps em out. Keep your home safe and secure with this added layer of protection.
- SPORTS ESSENTIAL PERFORMANCE AID AneCreams lidocaine cream is an essential companion for athletes, designed to provide fast-acting ease for sore body tissue, minor injuries, & irritations using its powerful 4% lidocaine blend. Its non-greasy, easy-to-apply texture ensures you apply it exactly where needed. Compact & portable, this lidocaine cream for pain fits everywhere, making it easy to carry wherever you go, hitting the gym, playing on the field, or traveling for competitions,
7. Dragon Maximum Strength Pain Relief Numbing Cream with Lidocaine, 2.7 Ounce

- Numbing Pain Relief Cream: This fact acting cream with 4 percent Lidocaine provides hours of maximum strength relief for aches and pains; It's odor free, with no irritation and no burning rub
- Deep Penetrating: This cream rapidly absorbs into the skin, providing fast relief for areas affected by muscle and joint aches and pains, arthritis or other discomfort for the back, knees, elbows and more
- Numbs Pain Fast: This fast-acting formula can be used up to 4 times a day to provide relief from minor muscle pain, including muscle strains, sprains, bumps, neck and backaches, and hands, joints and tendon pains
- Dragon Pain Relief Products: We carry a selection of analgesic products including patches, pain relief cream and pain numbing cream with lidocaine
- Dragon Pain Relief: We offer a selection of high-quality analgesic products with natural ingredients including gel, pain relief cream, and pain-numbing cream and patches with lidocaine, a topical anesthetic of rapid absorption and long duration
8. REVIVOL-XR 5% Lidocaine Numbing Cream (Non-Prescription OTC) Max Strength Dose (Topical External

- (External Topical Use) Highest Dose of 5% Lidocaine Available OTC, providing rapid relief from pain, itch, and burn associated with hemorrhoids, fissures, and other anorectal disorders. No Applicator as this is for external use only.
- Infused Powerful Antioxidants: Aloe Vera + Vitamin E added to help with soothing relief where you need it most.
- USA Lab Grade Standards: Manufactured in the USA by our regulated scientific lab.
- 3PL HRIPT Lab Study Passed: Plus, we rigorously test each batch to ensure that it meets our high standards for safety and effectiveness.
- Made in USA : Premium-grade Ingredients sourced Locally and worldwide, manufactured to the highest of standards, ensuring exceptional American quality.
9. Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Skin

- LIDOCAINE 5% PAIN CREAM MAXIMUM STRENGTH | Experience deep relief from skin pain with the strongest formulation of lidocaine, a topical anesthetic, on the market!
- MADE IN THE USA | A fast pain relief, anti itch, and numb cream - made with the highest quality, lab tested ingredients without the typical prescription mark-up.
- TREAT, NUMB & SOOTH ALL-IN-ONE | Our soothing, numbing cream provides fast relief from pain, itching, burning, discomfort & irritation by blocking the nerves and desensitizing your skin. Numbing relief for hemorrhoids and other anorectal issues.
- EXTRA LARGE 5% TOPICAL LIDOCAINE 6 OZ BULK TUBE | 50% more cream than your typical 4 oz lidocaine tube at a fraction of the cost. For external use only.
- CURIST PAIN RELIEF CREAM MAXIMUM STRENGTH | Stronger than Max Strength Aspercreme with 4% Lidocaine, typically used for arthritis, muscle pain, joint pain relief and as a tattoo numbing cream.
10. Bufferin Lidocaine 4% Numbing Cream with Hemp Seed Oil - Maximum Over-The-Counter- Strength Pain

- [ LIDOCAINE NUMBING CREAM ]: Fast-acting lidocaine cream with hemp for maximum over-the-counter strength pain relief. Topical cream for deep muscle pain. Hemp cream for hydrating the skin, providing lasting relief. Used as directed
- [ MAXIMUM STRENGTH PAIN RELIEF ]: This lidocaine numbing cream with hemp provides fast, targeted relief for deep muscle pain. Ideal hemp body lotion with Hemp Seed Oil for deep skin conditioning
- [ DAILY INTENSIVE CARE ]: Hemp pain relief cream designed for everyday use, offering soothing relief for muscle aches and pains. This hemp body lotion keeps skin conditioned and provides long-lasting comfort
- [ POWERFUL INGREDIENTS ]: Formulated with 4% lidocaine for maximum over-the-counter strength pain relief. This lidocaine cream soothes deep muscle pain, and provides daily intensive care
- [ EASY APPLICATION ]: Apply this lidocaine numbing cream with hemp to affected areas up to 3-4 times daily for up to 7 days. Ideal for maximum strength pain relief and deep muscle pain. Use as a daily intensive hemp cream for consistent relief
Peter
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