Best Otc Lidocaine Cream

Peter | 07-01-2026

Looking for some of the best Best Otc Lidocaine Cream? As you may know, there are dozens of brands available in the market such as HealthWise,Aspercreme,Curist,Thera Care and some come with vastly different price tags. Let us help you out here – we have handpicked the Best Otc Lidocaine Cream for you.

To compile our list, we’ve researched and evaluated a range of the best-selling products on the market. We recommend HealthWise Best Otc Lidocaine Cream as our top pick because of its exceptional overall performance. Want to explore more options? Read on! There’s also a buying guide to help you make a wise shopping decision.

Editor's Choice
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with
Premium Pick
HealthWise 4% Lidocaine Roll-On | OTC Strength | Pain Relief Liquid | 2.5 oz. 73 mL | Non-Greasy,
HealthWise 4% Lidocaine Roll-On | OTC Strength | Pain Relief Liquid | 2.5 oz. 73 mL | Non-Greasy,
Budget Pick
HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10%
HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10%

Top 10 Best Otc Lidocaine Cream

We researched and compared the top products in the Best Otc Lidocaine Cream category to provide you with these recommendations.

1. HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy
8.9

Healthwise

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  • MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • FAST-ACTING LIDOCAINE Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
  • SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Aspercreme with Lidocaine active ingredients
  • 2.7 oz. bottle (49.6g)

2. HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10%

HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10%
9.1

Healthwise

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  • MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • PAIN RELIEVING LIDOCAINE + BENZYL ALCOHOL Powerful pain relief ingredients: 4% lidocaine plus 10% benzyl alcohol work together by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA Non-greasy formula goes on smooth; safely apply 3-4 times daily
  • 30-APPLICATIONS PER TUBE Only a dime size of cream is needed per application to targeted areas for up to 30 applications in each tube
  • SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Salonpas Lidocaine Plus Pain Relieving Cream active ingredients
  • 3.0 oz. tube (85g)
  • Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
  • Always read detailed instructions before use

3. Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with
9.8

Aspercreme

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  • Contains one (1) 4.3-oz. tube of Aspercreme Pain Relief Cream With Max-Strength Lidocaine and Moisturizing Aloe
  • Fast-Acting Relief: Experience rapid and lasting pain relief with max-strength 4% lidocaine topical numbing cream, designed to target nerves and numb away pain
  • Non-greasy Formula: Fragrance-free Aspercreme moisturizes and relieves without greasy residue or strong odor
  • Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible
  • Travel-Size: Take your pain relief solution on the go in a compact and portable tube
  • Aspercreme is the topical lidocaine brand in the U.S.

4. Curist 5% Lidocaine Cream Maximum OTC Strength Topical Pain Relief OTC - 12 oz (Pack of 2) XL Tube 5

  • LIDOCAINE 5% PAIN CREAM MAXIMUM OTC STRENGTH | Experience deep pain relief with the strongest formulation of topical lidocaine on the market OTC
  • A pain relief and numbing cream - made with the highest quality, lab tested ingredients without the typical prescription mark-up. Made with globally sourced ingredients
  • TREAT, NUMB & SOOTH ALL-IN-ONE | Our soothing, numbing cream provides relief from pain, itching, burning, discomfort & irritation by blocking the nerves and desensitizing pain to provide numbing relief for hemorrhoids & other anorectal issues
  • EXTRA LARGE 5% TOPICAL LIDOCAINE 6 OZ BULK TUBE | 50% more cream than your typical 4 oz lidocaine tube at a fraction of the cost. For external use only
  • CURIST PAIN RELIEF CREAM MAXIMUM OTC STRENGTH | Stronger than the 4% lidocaine creams, which is typically used for tissue and muscle pain. Strongest lidocaine numbing cream available OTC

5. Thera|Care Maximum Strength OTC Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy

Thera|Care Maximum Strength OTC Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy
7.7

Thera Care

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  • MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • FAST-ACTING LIDOCAINE Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
  • SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Aspercreme with Lidocaine active ingredients
  • 1.75 oz. bottle (49.6g)
  • Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
  • Always read detailed instructions before use

6. Curist 5% Lidocaine Numbing Cream - 6 oz (170 g) XL Tube - Soothing Numbing Cream for Temporary

7. Curist 5% Lidocaine Cream Topical Pain Relief - Numb Quickly & Effectively with 5% Lidocaine Numbing

  • LIDOCAINE 5% PAIN CREAM | Experience deep pain relief with the strongest formulation of topical lidocaine available OTC.
  • A fast pain relief, anti itch, and numb cream - made with the highest quality ingredients without the typical pharmacy mark-up.
  • TREAT, NUMB & SOOTH ALL-IN-ONE | Our soothing, numbing cream provides fast relief from pain, itching, burning, discomfort & irritation by blocking the nerves and desensitizing. Numbing relief for hemorrhoids and other anorectal issues.
  • CURIST PAIN RELIEF CREAM | Stronger tha Aspercreme 4% Lidocaine, which is typically used for muscle pain and as a numbing cream.
  • EASY ACCESS JAR | Light, whipped formula for easy application. Get numbing relief at a fraction of the cost. For external use only.

8. WELMATE 5% Lidocaine Cream for Hemorrhoids, 6 oz Jar – Fast-Acting Lidocaine Numbing Cream &

  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.

9. Thera|Care Maximum Strength OTC Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy

Thera|Care Maximum Strength OTC Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy
7.9

Thera Care

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  • MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • FAST-ACTING LIDOCAINE Containing 4% lidocaine plus 1% menthol, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
  • SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to IcyHot Lidocaine Plus Menthol active ingredients
  • 1.75 oz. bottle (49.6g)
  • Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
  • Always read detailed instructions before use

10. HealthWise 4% Lidocaine Roll-On | OTC Strength | Pain Relief Liquid | 2.5 oz. 73 mL | Non-Greasy,

HealthWise 4% Lidocaine Roll-On | OTC Strength | Pain Relief Liquid | 2.5 oz. 73 mL | Non-Greasy,
9.5

Healthwise

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  • MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • FAST-ACTING OTC LIDOCAINE Containing 4% lidocaine, this liquid works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • ROLLER BALL STYLE APPLICATION Hands-free easy application keeps hands clean and dry; secure screw cap for convenient use on the go
  • NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
  • TIPS FOR SUCCESSFUL USE Lightly shake then flip the bottle upside down and glide over the skin, allowing the product to fully lubricate the rollerball while applying a thin, even layer of the product
  • SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Aspercreme Lidocaine Pain Relief Liquid active ingredients
  • 2.5 oz. roll-on application bottle (73 mL)

Peter

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