Best Enzyme Detergent

Peter | 28-12-2025

If you aren’t someone who makes frequent purchases, selecting the best Best Enzyme Detergent won’t be an easy chore for you. However, you shouldn’t be concerned because we have provided you with the most comprehensive list possible of the top Best Enzyme Detergent. Have a look at the products on our list, and pick the ones that appeal to you the most.

We researched and tested Best Enzyme Detergent in the market to get you this list. Our most recommended product is ACTIVE Best Enzyme Detergent. Check out our picks for all of our favorites, and be sure to read our buying guide to get all the information you need to make the best choice!

Editor's Choice
Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor
Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor
Premium Pick
Rockin’ Green Active Wear Laundry Detergent - Unscented Laundry Detergent Powder & Odor Eliminator
Rockin’ Green Active Wear Laundry Detergent - Unscented Laundry Detergent Powder & Odor Eliminator
Budget Pick
Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High
Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High

Top 10 Best Enzyme Detergent

We researched and compared the top products in the Best Enzyme Detergent category to provide you with these recommendations.

1. Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder,

  • Powerful Bio Enzymatic Cleaner: ACTIVE Laundry Odor Removers Boost your normal laundry detergent to effectively target Stains & Odors, not mask them like washing soda or in-wash scent boosters. It uses Lab-proven Biological Cleaning to remove laundry odor & strong smell
  • Heavy Duty Stain Remover for clothes: Our Enzyme Laundry Additive Powder is formulated for Stain Removal of dirty clothes, perfect for Funk, Grease, Armpit Sweat stain, Blood stain, Oil and more!
  • Gentle on All Fabrics: Our Fragrance Free Laundry Boost Plant-based Formula uses zero harsh chemicals. Natural enhancer for whites & colors. Even safe for pesky activewear fabrics
  • Value 64 Load Package: ACTIVE Enzyme Cleaner Concentrated 32-oz size is good for 64 Loads compared to other products with 1 lb or less
  • Compatible with all Washers & Detergents: Add Laundry Booster Powder to your usual detergent & cleaners! HE, Front & Top load Washer Approved. Also use as laundry soak pretreat powder in order to treat set-in stain

2. Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor

Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor
9.8

Nature's Miracle

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  • LAUNDRY BIO-ENZYMATIC FORMULA: Helps break down and destroy tough pet stains and odors, such as urine, feces, vomit, blood, grass and drool.
  • GENTLE ON FABRICS: Perfect for use on clothing, pet beds and morenot for use on specialty fabrics, including washable silk, khaki, fluorescents, wool, suede and leathers.
  • SAFE FOR PETS AND HOME: Formulated without phosphates, parabens, sulfates and bleach, this product is safe for use around pets and home, when used as directed.
  • ODORCAPTURE 360 TECHNOLOGY: An odor neutralizing system from Natures Miracle, the brand you trust because it works!
  • WORKS IN ALL MACHINES INCLUDING HE: Use in addition to your laundry detergent to help loosen and remove tough pet stains and odors.

3. Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High

Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High
9.1

Dirty Labs

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  • GENTLE: Our formula is consciously formulated with 100% bio and mineral-based ingredients. We left out all the harsh chemicals, fillers, toxins, and pollutants commonly found in other boosters to create a hyperefficient, nontoxic, biodegradable formula. We only use the good stuff so your body and the environment are left as clean as your detergent.
  • EFFECTIVE: Our advanced 4-in-1 formula is the first laundry product in the US to feature a groundbreaking bioenzyme that breaks down tough-to-remove biological stains and odors caused by sweat, body grime, and blood. (Think ring around the collar, yellow pit stains, weird grey or yellow stains on your favorite white sheets, and other stains.)
  • ENVIRONMENTALLY FRIENDLY: At Dirty Labs - Less is More. By creating hyper-concentrated formulas, we greatly reduce our package sizes (and thus, our carbon footprint). Our packaging is made of recyclable cardboard. Our scoop is made from responsibly sourced schima superba wood. Our materials are responsibly sourced and extracted directly from nature. We examine every aspect of our product life cycles in order to achieve the safest, most sustainable solutions.
  • DIRECTIONS: Follow your washer and garment care label instructions. For best results, use with Dirty Labs Bio Laundry Detergents. For standard and HE machines. Septic Safe. 1) Use laundry detergent as you normally would. 2) Add Bio Laundry Booster to wash drum before adding clothes.
  • SPECS: 480 g = 48 loads. Free & Clear (Scent Free). Compatible with traditional and HE washers. Optimized for cold water. No synthetic ingredients. Biodegradable formula. Hypoallergenic and safe for sensitive skin. Safe for babies and pets. Cruelty-free. Vegan. No sulfates. No dyes. No parabens and preservatives. No optical brighteners. No chlorine bleach. No 1,4-dioxane. No fragrance. No CA Prop. 65 chemicals. Packaging and formula are BPA-free.

4. OxiClean Odor Blasters Versatile Odor and Laundry Stain Remover Powder, 5 lb

OxiClean Odor Blasters Versatile Odor and Laundry Stain Remover Powder, 5 lb
8.9

Oxiclean

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  • One 5 lb box of OxiClean Odor Blasters Versatile Odor Eliminator and Stain Remover Powder laundry booster to get out tough stains and stubborn smells
  • Oxygen-based, water-activated laundry booster gets out tough dirt, persistent spots and set-in stains, plus eliminates sweat, musty towel and body odors with OxiClean stain remover
  • Works with regular detergent as a clothes stain remover and odor neutralizer to get clothes extra clean. For best results, use as a presoak before washing
  • This OxiClean powder stain and laundry odor remover can be used as a kitchen cleaner, bathroom cleaner, and fabric odor eliminator for machine-washable fabrics so you are ready for any mess
  • Tough on stains yet gentle on fabric, this chlorine-free, color-safe, fabric stain remover formula removes odors and stains to help keep the clothes you love look newer, longer

5. Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE

  • Concentrated Powder Detergent: ACTIVE Pet Detergent is a Powerful, High Efficiency Compatible Odor Destroyer & Stain Eliminating Detergent. Every Scoop has a Natural Cleaning Power to Handle any Mess, Stain, or Smell left behind by your pet.
  • Suitable for all Pet Laundry: Including Pet Bed, Clothing, Leash, Harness, Blankets, Towels, Furniture Covers & More! ACTIVE is an All-in-One Laundry Detergent Compatible With All Fabric Types, Even Use on your own Clothing and Bedding that smells like your pet!
  • Bio Based Enzyme Cleaner: ACTIVE Enzyme Laundry Detergent is Formulated to Target Pesky Stains and Odors, Including Pet Urine, Cat & Dog Pee, Vomit, Slobber, Dirt, Grime, Oils and Protein Stains. ACTIVE Enzymes even get rid of Wet Dog Odor, and others stubborn scents
  • Natural & Fragrance Free: ACTIVE Pet Detergent is a Natural Laundry Stain Remover, Free of Harsh Chemicals and Gentle for Pets and Sensitive Skin. ACTIVE Actually Removes Odors rather than using scents to cover them up like some alternatives
  • Best Value 64 Loads: Compare ACTIVE Dog Laundry Detergent to liquids that take up more space with less uses. Our Value Pack Comes in a Bulk 2 Lb bag so you can Keep Your Pet Laundry Taken Care Of!
  • Instructions for Use: First, Add 1 to 2 Scoops of ACTIVE Pet Laundry Detergent to your washing machine. Then add your pet laundry or other articles you wish to wash. Finally, start the appropriate washer program for the items you are cleaning. Note: this detergent powder is suitable for all water temperature settings including cold water, but some fabrics may be cleaned more effectively using Warm or Hot water options
  • Troubleshooting Guide: Some heavily soiled laundry items with pet stains or odors present may require extra treatment. We recommend pre-soaking your items in a tub of water, along with 1-2 scoops of detergent, for at least 2 hours. After the pre-soak, simply run through the washing machine like normal. You may also use one scoop of this detergent alongside your preferred laundry detergent for an extra boost of cleaning performance.

6. Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) |

Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) |
8.5

Dirty Labs

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  • GENTLE: Most cleaners today use technologies that were developed almost 100 years ago. In fact, many common deep-cleaning formulas still rely on harmful, petroleum-based chemicals. Dirty Labs is different. Consciously formulated with nontoxic, biobased ingredients, our formulas are safe for sensitive skin and all clothing types. Dirty Labs is cruelty-free, vegan, hypoallergenic, and safe for babies and pets.
  • EFFECTIVE: For us, dirty-free cleaning is not just about clean ingredients. We formulate to get the job done, and we put our products through rigorous testing to ensure theyre strong enough for those who like to get really dirty. Phytolase, our advanced enzyme cleaning technology targets stains and odors at their source while being extra gentle for you, your clothes, and the planet. But don't just take our word for it see what our customers are saying.
  • ENVIRONMENTALLY FRIENDLY: At Dirty Labs - Less is More. By creating hyper-concentrated formulas, we greatly reduce our package sizes (and thus, our carbon footprint). Our bottles are made of aluminum and can be infinitely recycled. Our ingredients are responsibly sourced and created through biorenewable manufacturing processes. We examine every aspect of our product life cycles in order to achieve the safest, most sustainable solutions.
  • DIRECTIONS: Follow your garment care label and washing machine instructions. Measure with teaspoon or Dirty Labs silicone beaker (available separately, or with all 32 load bottles). For tough stains, pretreat directly to soil area and allow to sit for 5 minutes before washing. Our detergent is hyper-concentrated use as follows: 8ml for medium loads, 12ml for large loads, 16 ml for x-large loads.
  • SPECS: 21.6 fl oz = 80 loads. Free & Clear (Scent Free). Compatible with traditional and HE washers. Optimized for cold water. Certified EPA Safer Choice Partner. 97% USDA Biobased certified. No sulfates, dyes, parabens, preservatives, chlorine bleach, or CA Prop.65 Chemicals. Visit our store for more ingredients information.

7. Lysol Tough Odor Eliminator Laundry Sanitizer Additive, Sanitizing Liquid for Gym Clothes and

  • LAUNDRY DETERGENT ADDITIVE: Add Lysol Laundry Sanitizer to every wash, in the fabric softener drawer, to sanitize and deodorize smelly laundry. Lysol Laundry Sanitizer kills many bad odors that detergents leave behind.
  • COLOR SAFE BLEACH ALTERNATIVE: Lysol Laundry Sanitizer is a bleach alternative that effectively kills 99.9% of bacteria, without the harshness of bleach. It's gentle on fabrics, effective in cold water, and is safe to use on colors and whites.
  • LYSOL LAUNDRY SANITIZER: Better than in-wash scent boosters that just mask bad odors. Lysol Laundry Sanitizer kills the odor causing bacteria that laundry detergents alone can leave behind, even in cold water Can be used in standard and HE machines.
  • ODOR ELIMINATOR FOR STRONG ODOR: Say goodbye to stubborn odors with Lysol Laundry Sanitizer, an advanced formula designed to act as an effective odor eliminator for even the toughest smells, leaving your clothes smelling fresh after every wash.
  • HOUSEHOLD ESSENTIALS and CLEANING SUPPLIES: Lysol is a leader in disinfection. Shop our range of household cleaning supplies including disinfectant wipes, toilet bowl cleaners, air sanitizers, and disinfectant sprays. The best protection is prevention
  • Kills 99.9% of Staphylococcus aureus and Klebsiella pneumonia on laundry.

8. Rockin’ Green Active Wear Laundry Detergent - Unscented Laundry Detergent Powder & Odor Eliminator

Rockin’ Green Active Wear Laundry Detergent - Unscented Laundry Detergent Powder & Odor Eliminator
9.5

Rockin' Green

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  • Breaks Down Sweat and Odors - Our activewear laundry detergent uses plant-based enzymes to tackle sweat, body oils, and odor at the source. A powerful laundry odor eliminator that keeps gym clothes, leggings, and workout gear fresh.
  • Protects Performance Fabrics - This sports laundry detergent is specially formulated to clean high-tech fabrics and microfibers while helping maintain stretch, breathability, and long-lasting wear so your favorite activewear stays in top condition, wash after wash.
  • Free from Harsh Additives - Our unscented laundry detergent is safe for sensitive skin when used as directed. Free from SLS, SLES, dyes, phosphates, parabens, and artificial fragrances, it keeps the clothes closest to your skin soft and comfortable after every wash.
  • Concentrated Cleaning Power - One 45 oz bag lasts up to 90 loads. Just 1 scoop of our athletic laundry detergent delivers a deep clean, while an extra scoop boosts odor removal. Works in all washing machines, including HE, making it convenient for both home laundry rooms and gym facilities. Doubles as a pre-soak.
  • Formulated with Care - Made with mineral- and plant-based ingredients in a GMP-certified facility, and never tested on animals. A thoughtful active wear laundry detergent designed to care for your clothes and your family.

9. ARM & HAMMER Super Washing Soda Household Cleaner and Laundry Booster, 55 oz Box

ARM & HAMMER Super Washing Soda Household Cleaner and Laundry Booster, 55 oz Box
8.9

Arm & Hammer

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  • One 55 oz box of ARM & HAMMER Super Washing Soda Household Cleaner and Laundry Booster
  • 100% fragrance-free and phosphate-free washing soda neutralizes and eliminates odors naturally without the use of heavy fragrances, leaving a long-lasting fresh and neutral clean scent
  • As a laundry additive, it improves liquid laundry detergent performance by up to 15% (1), giving you cleaner, whiter and brighter laundry and upholstery (1) For mustard and blood stains vs leading value detergent alone
  • Great general purpose cleaner for a wide variety of indoor and outdoor hard surfaces like sinks, stainless steel, bathtubs, garage floors and more, a must-have addition to your household cleaning supplies
  • Use as a silver polish to remove tarnish from silver, gold, brass or copper to keep your jewelry, silverware and precious items looking their best

10. Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet

  • STAIN AND ODOR REMOVER: Bac-Out safely works wonders on pet accidents, wine spills on carpets and couches, cloth diapers and pails, laundry, disposals, garbage cans and much more.
  • PREFERRED BY PROFFESSIONALS: Bac-Out is the preferred choice of commercial carpet cleaners nationwide.
  • BIO ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
  • PLANT BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
  • MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts

Peter

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