Best Cortisol Blocker

Peter | 06-01-2026

With so many Best Cortisol Blocker brands on the market – from big names like Dr. Matthew,Integrative Therapeutics,Optiwav,StrongVit,THORNE to smaller companies – finding the right product can be a real challenge. But we’re here to make your search easier.

We carefully researched and tested a vast range of Best Cortisol Blocker to help you discover the top contenders that match different needs and preferences. Altogether, we spent over 100 hours evaluating numerous products first-hand.

Our #1 best Best Cortisol Blocker is Dr. Matthew Best Cortisol Blocker, based on its stellar performance across all our tests. Below you’ll find more of our top-rated recommendations for great Best Cortisol Blocker options currently available. Make sure to check out our buying guide too – it’s full of expert advice for choosing a Best Cortisol Blocker tailored to exactly what you’re looking for. With our help guiding your decision, finding your perfect fit will be a breeze!

Editor's Choice
Cortisol Reducer & Adrenal Support Supplement–Natural Stress Relief with Ashwagandha KSM-66,
Cortisol Reducer & Adrenal Support Supplement–Natural Stress Relief with Ashwagandha KSM-66,
Premium Pick
Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep*
Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep*
Budget Pick
Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep*
Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep*

Top 10 Best Cortisol Blocker

We researched and compared the top products in the Best Cortisol Blocker category to provide you with these recommendations.

1. Cortisol Reducer & Adrenal Support Supplement–Natural Stress Relief with Ashwagandha KSM-66,

Cortisol Reducer & Adrenal Support Supplement–Natural Stress Relief with Ashwagandha KSM-66,
9.8

Dr. Matthew

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  • POWERFUL CORTISOL REDUCER & STRESS SUPPORT FORMULA: CortiRest is a natural cortisol reducer with KSM-66 Ashwagandha, Rhodiola Rosea, and L-Theanine key adaptogens shown to help lower cortisol levels and promote calm focus. Supports those searching for the best supplement to lower cortisol or a cortisol blocker for women and men seeking stress balance, relaxation, and mental clarity during demanding days, plus a gentle cortisol detox approach.
  • BEST SUPPLEMENTS TO LOWER CORTISOL & SUPPORT BALANCE: Combining Ashwagandha, Apigenin, and Magnesium, CortiRest helps maintain healthy cortisol rhythm, promoting emotional stability, steady energy, and relaxation. A favorite among natural cortisol reducers and cortisol blockers for women or men aiming to reduce high cortisol and support balanced hormones and overall stress response naturally. It's often compared to top adrenal support supplements.
  • NATURAL RELAXATION & NIGHT-TIME CORTISOL SUPPORT: L-Theanine and Magnesium Glycinate + Citrate promote relaxation and restful sleep without melatonin. Helps lower cortisol at night and reduce tension for morning energy and focus. Ideal for anyone searching for a nighttime cortisol reducer, low cortisol supplement, or natural way to lower cortisol levels and support deep relaxation and mental recovery.
  • CORTISOL BLOCKER FOR MEN & WOMEN ENERGY & WELLNESS SUPPORT: Vitamin D3 and Turmeric Extract (95% Curcuminoids) support immune function and energy while helping the body adapt to stress. Supports those seeking the best cortisol lowering supplement, cortisol reducer for weight management, or cortisol blocker for belly fat by supporting healthy metabolic balance and stress resilience without stimulants or hormones. ingredients.
  • PURE FORMULA YOU CAN TRUST BACKED BY SCIENCE: Made in an NSF-audited GMP facility and lab-tested for purity and potency. Vegan, non-GMO, free from gluten, dairy, soy or artificial additives. An all-natural cortisol reducer trusted by those seeking to reduce cortisol levels, support calm energy, and restore balance each day. Dr. Matthew CortiRest a science-driven formula for stress support and everyday composure.

2. Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep*

Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep*
9.8

Integrative Therapeutics

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  • Best Overall Ashwagandha Supplement*: For stress support, Cortisol Manager has been voted best overall Ashwagandha supplement as seen in Vogue*; it helps support balanced cortisol levels and a healthy response to everyday stress*
  • Relaxation Support*: Supports relaxation and calm to support restful sleep*
  • Supports Restful Sleep During Stress*: With ongoing use, this supplement with L-theanine and ashwagandha helps ease occasional sleeplessness disrupted by stress*
  • Integrative Therapeutics Cortisol Manager: Cortisol Manager does not contain gluten, wheat, or dairy
  • About Integrative Therapeutics: For over 25 years, patients and clinicians have trusted us for our dedication to quality, potency, and accuracy; transparency around our sourcing and manufacturing processes is part of our quality promise to you

3. Optiwav Cortisol Reducer Gummies for Women Men - 13-in-1 Daily Cortisol Detox Manager Supports

Optiwav Cortisol Reducer Gummies for Women Men - 13-in-1 Daily Cortisol Detox Manager Supports
9.1

Optiwav

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  • 13-in-1 Cortisol Support Formula: Optiwav Cortisol Gummies feature a potent Cortisol Support Blend, including Bacopa, Lions Mane, GABA, Holy Basil, and Ginseng, to help regulate high cortisol levels and promote a balanced mood and response to stress. This formula is enriched with Ashwagandha, L-Theanine, Phosphatidylserine, Magnolia Bark, Rhodiola, Magnesium Glycinate, and essential B vitamins, acting as a high cortisol detox manager for overall well-being.
  • Promotes Focus, Cognitive Sharpness & Clarity: With ingredients like L-Theanine, Phosphatidylserine, and Rhodiola Rosea, Optiwav Cortisol Reducer Gummies promote improved focus and cognitive performance. This blend supports sharper concentration and heightened alertness, making it easier to stay on task throughout the day. Whether at work or during study, the formula helps maintain clarity and productivity, ensuring consistent energy and focus for all daily activities.
  • Adaptogenic Ingredients for Stress Management: Optiwav Cortisol Gummies feature a powerful combination of adaptogens, including Bacopa Monnieri, Lions Mane Mushroom, Holy Basil, and Rhodiola Rosea, designed to help the body adapt to stress. These ingredients promote relaxation, improve resilience, and support overall well-being. This unique blend provides effective support for maintaining health and balance during stressful situations and helps promote calmness throughout the day.
  • Mixed Berry Flavor, Sugar-Free & Vegan: The delicious mixed berry flavor of Optiwav Cortisol Detox Supplements Gummies for Women and Men offers a refreshing and enjoyable way to support wellness. Sugar-free, vegan, and free from artificial sweeteners, colors, and flavors, these gummies provide a clean and natural formula. With no compromise on taste or quality, they fit seamlessly into any daily routine while supporting focus, mood, overall wellness, and a balanced response to stress.
  • GMP-Certified for Quality Assurance: Optiwav Cortisol Gummies are manufactured in a GMP-certified facility, ensuring the highest standards for safety, purity, and consistency. Each batch is crafted with care and precision, providing a reliable source of support to help reduce high cortisol levels, cognitive function, and overall wellness. With 60 gummies per bottle, providing a full 30-day supply, Optiwav Cortisol Gummies deliver effective, dependable daily support.

4. StrongVit Cortisol Supplements for Women and Men with Magnesium, Ashwagandha & L-Theanine. High

StrongVit Cortisol Supplements for Women and Men with Magnesium, Ashwagandha & L-Theanine. High
8.5

Strongvit

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  • 16-in-1 Extra Strength Supplement: Unlock a wave of relaxation with our powerful magnesium complex cortisol supplement. Featuring L-Theanine, Ashwagandha, Phosphatidylserine, and a blend of over 13 essential minerals, this unique formula is perfectly designed for a busy lifestyle. It promotes overall wellness, and helps effectively manage, reducer, and lower cortisol levels, stress relief, making it a top choice.
  • Transform Your Sleep Quality: Our expertly crafted formula combines Ashwagandha, L-Theanine, and Magnesium Glycinate to help you fall asleep quickly and wake up feeling rested. Embrace the restorative sleep you deserve with this non-habit-forming supplement, perfect for nightly use. Cortisol supplements for women and men contain minerals and vitamins that combine nutrients to help boost your overall well-being.
  • Holistic Cortisol Support: Experience comprehensive adrenal health, cortisol balance, while helping and reduce cortisol levels, with our all-in-one formula. Powered by adaptogens like Lion's Mane, Holy Basil, and Rhodiola Rosea, it supports your immunity. Enhanced with GABA and Phosphatidylserine, this supplement is the smart way.
  • Third-Party Lab Tested in the USA Our Cortisol supplement pills are rigorously tested by Swift Laboratory for purity and potency. Experience a 30-day supply bottle 2 capsules a day, filled with a powerful fusion of herbs and vitamins, GMO-free, Gluten-free and free from harmful chemicals. It not contains any allergens or sensitivities.
  • At StrongVit, your satisfaction is our top priority. We deliver premium products because you deserve the best. Moreover, we stand behind our products with a 100% money-back. If you're not delighted, rest assured you're fully covered by our no-questions-asked money-back. Just contact us through Amazon.

5. Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep*

Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep*
9.5

Integrative Therapeutics

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  • Best Overall Ashwagandha Supplement*: For stress support, Cortisol Manager has been voted best overall Ashwagandha supplement as seen in Vogue*; it helps support balanced cortisol levels and a healthy response to everyday stress*
  • Relaxation Support*: Supports relaxation and calm to support restful sleep*
  • Supports Restful Sleep During Stress*: With ongoing use, this supplement with L-theanine and ashwagandha helps ease occasional sleeplessness disrupted by stress*
  • Integrative Therapeutics Cortisol Manager: Cortisol Manager does not contain gluten, wheat, or dairy
  • About Integrative Therapeutics: For over 25 years, patients and clinicians have trusted us for our dedication to quality, potency, and accuracy; transparency around our sourcing and manufacturing processes is part of our quality promise to you

6. THORNE - Adrenal Cortex - Supplement for Cortisol Management - Support Healthy Adrenal Gland

  • Support For A High-Stress World: Lifestyle habits that deprive us of adequate rest and exercise, and poor dietary habits can, over time, take their toll on the adrenal glands
  • Adrenal support: Formulated with a unique extract to nourish the adrenal glands, which help regulate metabolism and the bodys stress response*
  • Promote energetic feelings: Helps maintain immune function and promotes an energetic feeling*
  • Stabilize stress hormone: Helps stabilize the stress hormone, cortisol, which naturally peaks in the morning and declines during the day too much stimulus (stress) can cause cortisol to get out of balance
  • Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

7. LES Labs Cortisol Health – Stress Relief, Balanced Cortisol Response, Relaxation & Deep Sleep –

LES Labs Cortisol Health – Stress Relief, Balanced Cortisol Response, Relaxation & Deep Sleep –
8.3

Les Labs

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  • Promotes balanced cortisol response and restful sleep: Drug-free formula promotes a balanced cortisol response to mental and physical stress and supports restful sleep.*
  • Natural ingredients: Natural formula including phosphatidylserine, magnesium, ashwagandha, magnolia, and rhodiola root extract.
  • Supports relaxation and helps reduce stress: Ashwagandha and rhodiola extracts help promote relaxation. Included magnesium provides an added calming effect.
  • Supports healthy cortisol levels: Formulated to support balanced cortisol response, a powerful hormone released during times of stress.
  • Try Cortisol Health and see how it works for you. At LES Labs we're 100% committed to making sure that you feel happy & healthy with your purchase - that's our promise to you. We manufacture all of our products in the USA with the highest-quality ingredients from around the world.

8. 10-IN-1 Cortisol Supplements w/ KSM-66® Ashwagandha 300mg + L-Theanine 250mg, Magnesium Glycinate,

  • The bottle you received is our newer 10-in-1 formula. We increased the blend from 636mg to 828mg per serving and upgraded ashwagandha to KSM-66 for a more consistent experience. Thanks for your understandingplease message us via Amazon with any questions.
  • 10-IN-1 CORTISOL SUPPLEMENTS: Our cortisol reducer combines KSM-66 Ashwagandha, L-Theanine, Magnesium Glycinate, Phosphatidylserine, Saffron, Turmeric and essential Vitamin C D B6 Pantothenic Acid (B5) to to support balance, calm, focus, and overall daily wellness.*
  • PREMIUM INGREDIENTS FOR BALANCE & WELL-BEING: Made with top-rated ingredients used in many adrenal support and stress relief supplements, including KSM-66 Ashwagandha 300mg, L Theanine 250mg, and Magnesium Glycinate. Designed to support relaxation, clarity, energy balance and overall wellness without harsh additives.*
  • DESIGNED FOR REAL LIFE, MADE FOR REAL PEOPLE: Whether youre juggling a demanding job, managing family responsibilities, pushing through workouts, or simply trying to stay balanced through everyday stress, this 10-in-1 cortisol manager formula fits naturally into your routine. Ideal for professionals needing focus, busy parents seeking calm, students looking for mental clarity, and anyone wanting smoother days and more peaceful nights.*
  • 60-DAY SUPPLY - CUSTOMIZE YOUR ROUTINE: With 120 capsules, you get a full 60-day supply. Choose the timing that fits your goals: 1) Daytime balance & focus: Take 2 capsules with breakfast. 2) Mood & daytime support: Take 1 capsule in the morning + 1 with lunch. 3) Evening calm & restful nights: Take 2 capsules with dinner or 12 hours before bed. Stay consistent for best results.*
  • CLEAN & NATURAL INGREDIENTS: Made with high-potency ingredients and free of gluten, soy, dairy, nuts, sugar, preservatives, and artificial fillers. You get a pure, clean formula you can feel confident taking. Third-party tested for quality and safety.*
  • YOUR WELLNESS SUPPORT MATTERS: We want you to have a positive experience with our cortisol support supplement. If you need help choosing the best routine or have questions about your wellness goals, our support team is here for you.

9. Nugenix Cortisol Control - Cortisol Manager and Adrenal Support Supplement for Men, 60 Capsules

Nugenix Cortisol Control - Cortisol Manager and Adrenal Support Supplement for Men, 60 Capsules
7.9

Nugenix

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  • Too much cortisol can counteract the body's internal balance. Keep your cortisol levels in check with Nugenix Cortisol Control.
  • Our powerhouse formula was carefully designed with 6 key ingredients, including patented Sensoril and Relora, to help maintain healthy cortisol levels and enhance the body's resistance to stress.
  • When used daily, Nugenix supports adrenal health; increases feelings of energy, vitality and positive mood; and relieves anxiousness, tension and stress-related fatigue
  • Nugenix Cortisol Control is manufactured under strict FDA Guidelines for Good Manufacturing Practices and is made without gluten, soy, GMOs, artificial flavors, hormones, or harmful fillers
  • Our science-backed cortisol control formula can be stacked with any other product in the Nugenix line for enhanced male benefits

10. Cortisol Supplement for Women and Men — Calm, Balanced-Strength 5-in-1 Non-Drowsy, Third-Party

  • Designed, Not Piled on: Calm, Balanced-Strength 5-in-1, non-drowsy.
  • Standardized Bioactives, Stated MG: Ashwagandha 25% (500 mg), PS 250 mg, L-Theanine 200 mg, Mg (glycinate) complex 750 mg and Rhodiola 3%/1% (300 mg).
  • Gentle Where it Matters: Mg glycinate + L-Theanine for calm focus; day or night.
  • Transparent by Design: No blends, every mg listed. 120 capsules = 30-day program.
  • Third-Party Tested, Lot by Lot: Raw and finished: identity, potency, heavy metals, micro, fill-weight (results on request).

Peter

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