Best Numbing Gel

Peter | 28-12-2025

Navigating the many Best Numbing Gel options on the market – from major brands like WELMATE,Ebanel,HealthWise,Neosporin,EBANEL LABORATORIES to lesser-known names – can feel overwhelming. But we’re here to help simplify your search for the best products.

After extensive research testing hundreds of Best Numbing Gel, we’ve selected the top contenders. Our number one recommendation is WELMATE Best Numbing Gel based on its stellar performance and quality. Below you’ll find more of our top-rated picks for the best Best Numbing Gel currently available.

Be sure to consult our handy buying guide as well for expert tips on choosing the right Best Numbing Gel to suit your individual needs. It has all the crucial information you need to make an informed purchasing decision. With our guidance backing your choice, finding your perfect match will be smooth sailing!

Editor's Choice
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical
Premium Pick
Lidocaine Jelly 2% Numbing Gel for Burn Relief 30ml - Sunburn Relief with Lidocaine, Topical for
Lidocaine Jelly 2% Numbing Gel for Burn Relief 30ml - Sunburn Relief with Lidocaine, Topical for
Budget Pick
Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal
Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal

Top 10 Best Numbing Gel

We researched and compared the top products in the Best Numbing Gel category to provide you with these recommendations.

1. WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical

WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical
9.1

Welmate

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  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.

2. Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical

  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
  • 5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Enhanced Liposomal Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
  • Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

3. HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10%

HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10%
9.1

Healthwise

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  • MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • PAIN RELIEVING LIDOCAINE + BENZYL ALCOHOL Powerful pain relief ingredients: 4% lidocaine plus 10% benzyl alcohol work together by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA Non-greasy formula goes on smooth; safely apply 3-4 times daily
  • 30-APPLICATIONS PER TUBE Only a dime size of cream is needed per application to targeted areas for up to 30 applications in each tube
  • SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Salonpas Lidocaine Plus Pain Relieving Cream active ingredients
  • 3.0 oz. tube (85g)
  • Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
  • Always read detailed instructions before use

4. HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy |

HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy |
8.9

Healthwise

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  • MAXIMUM STRENGTH RELIEF Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • FAST-ACTING LIDOCAINE Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
  • SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Aspercreme with Lidocaine active ingredients
  • 1.75 oz. bottle (49.6g)
  • Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
  • Always read detailed instructions before use

5. Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, Fast-Acting, Maximum Strength Topical

Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, Fast-Acting, Maximum Strength Topical
7.9

Neosporin

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  • Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, by the #1 doctor-recommended brand, has an effective germ-killing formula for 24-hour long-lasting infection protection and fast-acting numbing pain relief for minor wounds
  • Pain relief ointment formulated with triple antibiotic combination of infection-protection ingredients bacitracin zinc, neomycin sulfate and polymyxin B sulfate to help prevent infections in minor cuts, scrapes, and wounds for minor wound care treatment
  • Triple antibiotic ointment also contains fast-acting lidocaine, a topical analgesic that numbs away the pain, for maximum-strength burn pain relief and long-lasting infection protection from painful minor cuts, scrapes, burns, and wounds
  • First aid essential in a compact and portable 0.5-ounce tube, suitable in wound care supplies and first aid kits for home, on-the-go, cars, dorms, travel, camping, and outdoors, provides effective triple antibiotic protection for treatment of minor wounds
  • To use, clean affected area with a BAND-AID Brand Antiseptic Spray and treat with a small amount of first aid topical antibiotic ointment one to three times daily. Cover the minor wound with a BAND-AID Brand Adhesive Bandage for extra protection

6. Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical

Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical
7.9

Ebanel Laboratories

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  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb spray enhanced with 0.25% Phenylephrine HCl and Allantoin, temporarily relieves pain, burning, itching, and discomfort, reduces swelling, inflammation, soreness, and protects irritated skin in local and anorectal areas
  • 5% Lidocaine Spray Maximum Strength - This pain relief anti itch spray provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Enhanced Liposomal Deep Penetrating Pain Relief Spray - Best efficacy, fast-acting & long-lasting. It begins numbing in 2-3 minutes, peaks after 5-10 minutes, and lasts for 1 hour from its peak. Numbing performance may vary depending on the thickness of skin area, and individual metabolism
  • Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply during and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy, hands-free application. No need to remove it after
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

7. XESSO Anal Desensitizing Lube 8.3 Fl Oz, Water-Based Lubricant Rear Comfort Glide for Men, Women &

  • Quick, Effective and pH-Balanced: The 4% numbing agent helps to ease the pain, soreness, and burning, without compromising any other sensations; The effect kicks in fast enough to keep the action fluent and coherent; The formula is pH-balanced (value: 5.5-6) to match the body's natural chemistry and for anal use
  • Rear Comfort: The jellylike consistency is perfect for rear comfort, as the anus doesn't self-lubricate; It keeps the right area optimally wet and slippery, providing a smooth glide for a satisfying period; The glide is unscented, unflavored, and free of hormones, spermicide, PEGs, oil, animal products, and animal testing
  • Non-Staining: Easily washable with running water and mild detergent, this non-staining lubricant won't leave a mess behind
  • American Made Quality: Manufactured in a GMP-compliant facility in California, ensuring top-quality American-made products
  • Discreet Packaging: We carefully wrap the product in opaque shrink sleeves to protect your privacy; Simply follow the dotted line to remove the opaque shrink sleeve and reveal the product inside before use
  • Package May Vary: Our commitment to consistency ensures the same trusted formula in every bottle; Packaging may vary as we continually refine our labels for greater clarity and accuracy in product information; Enjoy the same outstanding experience, every time

8. tuiwaro Numbing Cream Extra Strength: Relief Long Lasting & Fast-Absorbing with Emu Oil and Arnica

tuiwaro Numbing Cream Extra Strength: Relief Long Lasting & Fast-Absorbing with Emu Oil and Arnica
9.1

Tuiwaro

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  • EXTRA STRENGTH, LONG-LASTING RELIEF Fast-absorbing formula delivers lasting comfort for hours* without greasy residue. *Individual results may vary.
  • EMU OIL + ARNICA Skin-calming botanicals to condition and soothe the feel of skin.
  • LIGHT CREAM-GEL TEXTURE Deep yet lightweight absorption; smooth, even glide; no sticky feel, no stains on clothes.
  • EASY, PRECISE APPLICATION Black tube with safety seal and narrow tip for mess-free, even layers; a little goes a long way; 50 mL (1.7 fl oz).
  • FOR DAILY SKIN CARE Use before or after at-home beauty routines; suitable for face & body (external use only). Patch test recommended.

9. Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal

Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure - Ideal
9.5

Dr Care

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  • BEST NUMBING CREAM Designed for deep skin Numbing and comfort, Dr. Care Tattoo Cream helps prepare skin for tattoos and other beauty treatments.
  • SKIN-SOOTHING INGREDIENTS Contains Emu Oil, Arnica, Aloe vera and vitamin E to calm and support the skins natural balance, plus Aloe Vera and Vitamin E for hydration and softness.
  • MULTI-PURPOSE CREAM Ideal for tattoos, microblading, laser hair removal, waxing, and more; provides a soothing effect before, during and after treatment.
  • FAST-ABSORBING, NON-GREASY FORMULA Smooth, clean application with no sticky residuegreat for professional and at-home use.
  • GENTLE & VEGAN-FRIENDLY Free from harsh chemicals, cruelty-free, and suitable for all skin types. A must-have for your tattoo or cosmetic prep routine.

10. Lidocaine Jelly 2% Numbing Gel for Burn Relief 30ml - Sunburn Relief with Lidocaine, Topical for

Lidocaine Jelly 2% Numbing Gel for Burn Relief 30ml - Sunburn Relief with Lidocaine, Topical for
9.5

Jelcaine Sterile

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  • FAST AND EFFECTIVE PAIN RELIEF WITH LIDOCAINE GEL: Jelcaine Sterile is a powerful lidocaine gel, offering fast and effective pain relief for cuts, scrapes, insect bites, sunburn, or other skin irritations. Whether you need burn relief gel for a recent burn or a numbing gel for itchy, irritated skin, Jelcaine works quickly to reduce discomfort, helping you get back to your day. An essential addition to your medicine cabinet, including burn gel and burn dressing.
  • QUALITY STERILE AND SAFE PACKAGING: Jelcaine Sterile comes in a 30ml tube pre-packaged in a sealed, sterile pouch, ensuring hygiene and safety with every use. Our sterilized packaging is great for those seeking sunburn relief in sterile burn gel packets to relieve pain. Whether using topical lidocaine for sensitive skin areas or burn relief, you can be confident in a safe, clean application each time.
  • TARGETED APPLICATION WITH PRECISION CONE: Our topical anesthetic sterile precision cone allows for accurate application of Jelcaine Sterile to the affected area. Ideal for sunburn relief, minor burns, or itchy skin, the precision cone ensures focused relief where you need it most including sensitive, intimate and discreet areas including use a topical, vaginal Lidocaine gel. . Jelcaine topical anesthetic gel also works well for providing pain relief to sensitive areas of your body.
  • INSTANT AND MULTIPLE PAIN RELIEF USES: Jelcaine Sterile topical pain relief solution offers quick alleviation and numbing for numerous pain and itch-related problems. It temporarily relieves discomfort from minor cuts, sunburn, minor scrapes, minor burns, insect bites, and skin irritations. It provides intimate pain relief for sensitive areas. Our lidocaine gel is odor-free, cooling, unscented, greaseless, and water-soluble, offering smooth, moisturizing application without sticky residue.
  • CONVENIENT, PORTABLE, AND HSA/FSA ELIGIBLE: Our 30ml tube of Jelcaine Sterile offers a convenient and portable solution for ongoing pain relief. Ideal for home use or on-the-go, it provides a cost-effective, versatile and reliable option for sunburn relief, minor burn care, and itchy skin relief. Plus, its eligible for HSA and FSA purchases, helping you save while stocking up on this essential pain relief product. OTC products eligible without a prescription.

Peter

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