Best Dao Enzyme

Peter | 25-12-2025

Looking for some of the best Best Dao Enzyme? As you may know, there are dozens of brands available in the market such as SOLARAY,GREAT BILLIOM,Life Extension,NATURALABS,Seeking Health,Healthy Gut and some come with vastly different price tags. Let us help you out here – we have handpicked the Best Dao Enzyme for you.

To compile our list, we’ve researched and evaluated a range of the best-selling products on the market. We recommend SOLARAY Best Dao Enzyme as our top pick because of its exceptional overall performance. Want to explore more options? Read on! There’s also a buying guide to help you make a wise shopping decision.

Editor's Choice
SOLARAY DAO Enzyme - Digestive Enzyme That Breaks Down Histamine - 60,000 HDU - Digestive Enzymes -
SOLARAY DAO Enzyme - Digestive Enzyme That Breaks Down Histamine - 60,000 HDU - Digestive Enzymes -
Premium Pick
GREAT BILLIOM DAO Enzyme (Diamine Oxidase) - Digestive Enzymes for Women & Men - 30,000 HDU - Gut
GREAT BILLIOM DAO Enzyme (Diamine Oxidase) - Digestive Enzymes for Women & Men - 30,000 HDU - Gut
Budget Pick
Life Extension Food Sensitivity Relief with Diamine Oxidase (DAO), Occasional Gas, Digestive
Life Extension Food Sensitivity Relief with Diamine Oxidase (DAO), Occasional Gas, Digestive

Top 10 Best Dao Enzyme

We researched and compared the top products in the Best Dao Enzyme category to provide you with these recommendations.

1. SOLARAY DAO Enzyme - Digestive Enzyme That Breaks Down Histamine - 60,000 HDU - Digestive Enzymes -

SOLARAY DAO Enzyme - Digestive Enzyme That Breaks Down Histamine - 60,000 HDU - Digestive Enzymes -
9.8

Solaray

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  • Digest Histamine DAO (or Diamine Oxidase) is an enzyme that is naturally present in the gut and plays an important function in metabolizing dietary histamine ingested from food.*
  • Powerfully Potent Solaray DAO Enzyme supplements are plant sourced from pea sprouts and are designed to supply 60,000 HDU, or Histamine Degradation Units.
  • Enteric Shield Our DAO supplement is made with an enteric coated capsule, which helps the ingredients survive the stomach acid and pass into the small intestine for better utilization.*
  • Making a Difference - To reduce our carbon footprint, Solaray bottles are made from post-consumer recycled resin, helping keep plastic out of our landfills and oceans; weve also installed solar panels as an additional energy source at our Ogden, Utah facilityto power the processes and products that help you Live Brighter.
  • Trusted Brand - Vegan, made in our GMP-certified facility, and always tested in our own state-of-the-art lab in Utah to bring you the best possible quality.

2. GREAT BILLIOM DAO Enzyme (Diamine Oxidase) - Digestive Enzymes for Women & Men - 30,000 HDU - Gut

GREAT BILLIOM DAO Enzyme (Diamine Oxidase) - Digestive Enzymes for Women & Men - 30,000 HDU - Gut
9.5

Great Billiom

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  • MAX STRENGTH DAO ENZYME (DIAMINE OXIDASE): High-potency DAO enzyme standardized to at least 30,000 HDU per capsule to support dietary histamine metabolism, comfortable digestion, and everyday gut health. Powerful digestive enzymes for women & men; this DAO supplement is a top choice among digestive enzymes and enzymes for digestion.*
  • STANDARDIZED & PROTECTED: Provides 4.2 mg DAO from porcine kidney extract (diamine oxidase) standardized in HDU for consistent DAO enzyme activity. Delayed-release HPMC capsule helps protect in stomach and deliver to the intestine for dietary histamine support, convenient DAO capsules are an addition to digestive enzymes & enzymes for digestion.*
  • SUPPORT FOR HIGH-HISTAMINE FOODS: Take dao enzyme supplements with fermented foods, especially pizza, aged cheese, red wine or beer, and cured meats, to support dietary histamine metabolism and comfortable digestion. A Leader among gut health supplements and any digestion supplement routine.*
  • EASY TO TAKE DAILY: Take 1 delayed-release capsule 10 to 15 minutes before meals, up to 3 times daily. This enzymes for digestion (Diamine Oxidase) provides 30,000 HDU per capsule; 60 capsules per bottle. Supports dietary histamine breakdown and mealtime digestive comfort.*
  • RELIABLE BRAND: Great Billiom is an American nutrition supplement brand dedicated to providing premium supplements for optimal health. Our DAO Enzyme (Digestive Enzymes) supplement is crafted to rigorous quality standards to deliver dependable support for gut health supplements routines and any digestion supplement plan. If you are unsatisfied with the product for any reason, we're happy to do everything to make it right! Individuals with a known medical condition or allergies should consult a physician before using this or any dietary supplement.

3. Life Extension Food Sensitivity Relief with Diamine Oxidase (DAO), Occasional Gas, Digestive

Life Extension Food Sensitivity Relief with Diamine Oxidase (DAO), Occasional Gas, Digestive
9.1

Life Extension

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  • Gastrointestinal comfort Get relief from occasional gas and stomach upset, as well as other gastrointestinal discomforts caused by histamine-rich foods like cured meats, cheese and wine
  • Histamine metabolism Diamine oxidase supports the healthy breakdown of intestinal histamine. This in turn helps relieve occasional non-allergy digestive discomfort associated with dietary histamine sensitivity.
  • Plant-based DAO Many DAO formulas utilize enzymes derived from animals (usually pork). But our formula uses diamine oxidase from pea sprouts.
  • Ingredients matter We use the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USAand a Certificate of Analysis is available for every one.
  • Live your healthiest life We believe the answers to a healthier life are in reach, and that scientific research is the key to getting there. Thats why so many of our formulas feature specific ingredients and amounts based on scientific studies.

4. NATURALABS DAO Supplements Histamine Blocker – DAO Enzyme + Diamine Oxidase & Vitamin C for Gut

NATURALABS DAO Supplements Histamine Blocker – DAO Enzyme + Diamine Oxidase & Vitamin C for Gut
8.9

Naturalabs

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  • Support for Histamine Balance Take 1 capsule before meals to help your body process food-derived histamine naturally. Each capsule delivers 10,000 HDU of active DAO sourced from porcine. Crafted thoughtfully so you can enjoy your meals to the fullest.
  • Gentle Gut Support After Meals Helps ease discomfort like bloating, stuffy nose, or post-meal unease caused by histamine intolerance. This formula is crafted to help your gut respond more smoothly.
  • Vitamin C for Better Absorption Supports DAO enzyme performance and nutrients absorption for optimized histamine breakdown, making DAO Enzyme+ digest and immune support supplement a smart addition to your daily health routine.
  • Clean Formula, Trusted Quality DAO Enzyme+ is Non-GMO, gluten-free, and made in the USA in an FDA-registered facility with no artificial fillers or unnecessary additives.
  • Smart Supplement for Daily Use DAO Enzyme+ brings together nature and science to support your bodys ability to manage everyday food reactions - without unnecessary ingredients or complexity.

5. Seeking Health DAO Enzyme - Formerly Histamine Digest, DAO Enzyme Supplement for Histamine Food

Seeking Health DAO Enzyme - Formerly Histamine Digest, DAO Enzyme Supplement for Histamine Food
8.7

Seeking Health

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  • Digestive Enzyme Support: This digestion supplement formulated with patented DAO2 enzyme supports the healthy breakdown of histamine in many areas of your body
  • Fast-Acting Stomach Relief: For digestion support, take one supplement capsule just prior to consuming high histamine foods or drinks
  • Digest Histamine Support: This digestive enzyme supplement supports histamine already within a healthy range in the small intestines, colon, uterus, bladder, prostate and breast milk
  • Allergen-Friendly Gut Health Support: This histamine intolerance supplement is free of gmos, gluten, eggs, fish, shellfish, tree nuts, peanuts, wheat, sesame, and soy
  • Optimizing Healthy Living: From research to packaging, Seeking Health prioritizes quality and safety at every step of the production process to provide health support you can trust

6. Healthy Gut HistaHarmony | Delayed Release DAO Enzyme Supplement | 30,000 HDU Diamine Oxidase

Healthy Gut HistaHarmony | Delayed Release DAO Enzyme Supplement | 30,000 HDU Diamine Oxidase
8.5

Healthy Gut

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  • Supports Histamine Balance: Helps your body break down histamine from food, promoting a more comfortable digestive experience. HistaHarmony lets you enjoy even a glass of wine without histamine-related headaches.
  • Fast-Acting DAO Supplements Histamine Blocker: Designed for quick absorption with 30,000 HDU of Diamine Oxidase, so you can enjoy your meals again without the worry of histamine overload.
  • Advanced Enzyme Technology: Features ProDAOX for enhanced enzymatic activity and efficient histamine metabolism.
  • Gut-Friendly & Gentle: Enteric-coated tablets protect the enzyme, ensuring effectiveness without any stomach discomfort.
  • Quality You Can Trust: Free from artificial additives, gluten, and dairy, and made with high safety and purity standards.

7. Bravado Labs DAO Supplements Histamine Blocker – Extra Potent 30,000 HDU DAO Enzyme Formula for

Bravado Labs DAO Supplements Histamine Blocker – Extra Potent 30,000 HDU DAO Enzyme Formula for
8.3

Bravado Labs

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  • Tired of food ruining your day? Our doa supplements histamine blocker helps you enjoy wine, cheese, or shellfish againwithout the bloating, sneezing, or regret.
  • Stop histamine from stealing your comfort. This histamine intolerance supplement supports your bodys natural breakdown process, easing reactions to high-histamine foods.
  • Powered by science, packed with DAO. Each dao enzyme supplement capsule delivers 30,000 HDUsupporting a stronger histamine block from the first use.
  • Say goodbye to post-meal misery. Our DAO enzyme supplements are designed for smoother histamine digest, helping you breathe easier and feel lighter after every bite.
  • Why settle for less DAO? This premium dao enzyme formula is a high-potency solution trusted by those needing reliable dao supplements histamine blocker performance.

8. Designs for Health HistaGest-DAO - Diamine Oxidase DAO Enzyme to Support Digestion of

Designs for Health HistaGest-DAO - Diamine Oxidase DAO Enzyme to Support Digestion of
8

Designs For Health

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  • Support Digestion of FoodDerived Histamines - Lower DAO activity may result in higher levels of histamine being absorbed through the small intestine and accumulating in the blood. HistaGest-DAO provides supplemental diamine oxidase enzyme. Unlike common digestive enzyme products, this enzyme is responsible for breaking down food-derived histamine to help support normal and healthy histamine metabolism.*
  • Convenient 'Take-Anywhere' Dispenser - This DAO supplement offers small tablet delivery in a convenient travel dispenser for portability and ease of use when onthego. Each tablet provides 20,000 histamine-degrading units (HDU) of diamine oxidase (DAO) from porcine kidney extract to promote the degradation of dietary histamines.*
  • Just Take One Before Histamine-Rich Foods - Taking one diamine oxidase DAO supplement tablet before each meal promotes the amount of DAO in the small bowel to help break down histamine in the digestive tract, support digestive health and soothe digestive discomfort associated with sensitivity to histamine-rich foods.*
  • Delayed-Release Tablets Designed for High Performance - DAO supplements can be less effective if they do not reach the small intestine. HistaGest-DAO diamine oxidase supplement is made with gastro-resistant, coated tablets with delayed-release technology that allows the DAO enzyme to reach the small intestine where it performs its action.*
  • Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**

9. Seeking Health DAO Enzyme – Formerly Histamine Digest, DAO Enzyme Supplement for Histamine Food

Seeking Health DAO Enzyme – Formerly Histamine Digest, DAO Enzyme Supplement for Histamine Food
7.9

Seeking Health

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  • Supports Histamine Digestion: DAO Enzyme supplement designed to support the breakdown of histamine from foods and drinks, helping promote digestive comfort and balance.
  • Fast-Acting Relief: Take one capsule before consuming high-histamine foods or beverages for optimal digestive enzyme support.
  • Contains Porcine Kidney Extract: Each capsule contains DAOgest, a natural enzyme derived from porcine (pig) kidney extract, providing Diamine Oxidase (DAO) activity to help support histamine metabolism.
  • Allergen-Friendly Formula: Free from GMOs, gluten, eggs, fish, shellfish, tree nuts, peanuts, wheat, sesame, and soy.
  • Quality You Can Trust: Manufactured by Seeking Health, with a focus on purity, safety, and scientifically backed formulations to support healthy living.

10. Pure Encapsulations DAO Enzyme - Histamine Breakdown Digestion Support Supplement* - Ease Digestive

Pure Encapsulations DAO Enzyme - Histamine Breakdown Digestion Support Supplement* - Ease Digestive
7.7

Pure Encapsulations

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  • Histamine Digestion Support: Pure Encapsulations DAO Enzyme delivers diamine oxidase from porcine kidney extract to support dietary histamine breakdown, easing overall digestive discomfort*
  • Skin Sensitivity Relief: This gluten-free, hypoallergenic health supplement supports healthy dietary histamine levels, minimizes related skin flushing and sensitivity, and helps manage histamine intolerance symptoms*
  • Respiratory Symptom Relief: These unflavored vegetarian capsules offer comprehensive gut health support while relieving respiratory symptoms and stomach gas so you can eat with greater confidence*
  • Pure Quality: Made with premium ingredients sourced from trusted suppliers, our berberine capsules are carefully manufactured and tested for purity and potency
  • Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs

Peter

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