Best Pancreatic Enzymes

Peter | 25-12-2025

If you aren’t someone who makes frequent purchases, selecting the best Best Pancreatic Enzymes won’t be an easy chore for you. However, you shouldn’t be concerned because we have provided you with the most comprehensive list possible of the top Best Pancreatic Enzymes. Have a look at the products on our list, and pick the ones that appeal to you the most.

We researched and tested Best Pancreatic Enzymes in the market to get you this list. Our most recommended product is Vital Nutrients Best Pancreatic Enzymes. Check out our picks for all of our favorites, and be sure to read our buying guide to get all the information you need to make the best choice!

Editor's Choice
Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with
Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with
Premium Pick
Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with
Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with
Budget Pick
NOW Foods Supplements, Pancreatin 2000 with naturally occurring Protease (Protein Digesting),
NOW Foods Supplements, Pancreatin 2000 with naturally occurring Protease (Protein Digesting),

Top 10 Best Pancreatic Enzymes

We researched and compared the top products in the Best Pancreatic Enzymes category to provide you with these recommendations.

1. Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with

Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with
9.8

Vital Nutrients

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  • Premium Digestive Enzyme Supplement: Supports gut health, digestion, and bowel regularity with one easy-to-swallow capsule taken with meals. Helps support relief from occasional indigestion, gas, and bloating*
  • Full-Strength Pancreatic Enzymes For Humans Healthy Digestion: Lactose-free pancreatin includes protease, lipase enzymes, and amylase enzymes to support digestion and nutrient absorption from protein, fats, and carbohydrates*
  • Clean Formula: Free from gluten, dairy, peanut, tree nut, fish, shellfish, soy, sesame, and egg. Non-GMO. Made without artificial fillers, coatings, binders, or colors.
  • Quality You Can Rely on: Vital Nutrients supplements are manufactured in our allergen-free, NSF-certified Middletown, CT facility. Our rigorous quality assurance program includes third-party independent laboratory testing of raw ingredients and finished products for purity and potency to ensure whats on the label matches whats in the bottle
  • Trusted by Healthcare Practitioners Worldwide: Vital Nutrients was founded 30 years ago by practitioners who set out to make a positive and lasting impact on the health of people and planet. Today, our premium line of clinically relevant, pure, clean-label formulas is trusted by healthcare practitioners and health-conscious consumers worldwide

2. Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with

Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with
9.5

Vital Nutrients

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  • Premium Digestive Enzyme Supplement: Supports gut health, digestion, and bowel regularity with one easy-to-swallow capsule taken with meals. Helps support relief from occasional indigestion, gas, and bloating*
  • Full-Strength Pancreatic Enzymes For Humans Healthy Digestion: Lactose-free pancreatin includes protease, lipase enzymes, and amylase enzymes to support digestion and nutrient absorption from protein, fats, and carbohydrates*
  • Clean Formula: Free from gluten, dairy, peanut, tree nut, fish, shellfish, soy, sesame, and egg. Non-GMO. Made without artificial fillers, coatings, binders, or colors
  • Quality You Can Rely on: Vital Nutrients supplements are manufactured in our allergen-free, NSF-certified Middletown, CT facility. Our rigorous quality assurance program includes third-party independent laboratory testing of raw ingredients and finished products for purity and potency to ensure whats on the label matches whats in the bottle
  • Trusted by Healthcare Practitioners Worldwide: Vital Nutrients was founded 30 years ago by practitioners who set out to make a positive and lasting impact on the health of people and planet. Today, our premium line of clinically relevant, pure, clean-label formulas is trusted by healthcare practitioners and health-conscious consumers worldwide

3. NOW Foods Supplements, Pancreatin 2000 with naturally occurring Protease (Protein Digesting),

NOW Foods Supplements, Pancreatin 2000 with naturally occurring Protease (Protein Digesting),
9.1

Now Foods

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  • DIGESTIVE SUPPORT: Pancreatin has naturally occurring protease (protein digesting), amylase (carbohydrate digesting), and lipase (fat digesting) enzymes.
  • ASSISTS PROTEIN, FAT, AND CARBOHYDRATE DIGESTION: Pancreatin is a preparation of porcine pancreatic enzymes.
  • CERTIFICATIONS/CLASSIFICATIONS: Keto Friendly, Soy Free, Nut Free, Made without Gluten, Dairy Free, Egg Free
  • Digestive
  • Family Owned Since 1968

4. Pure Encapsulations Pancreatic Enzyme Formula - Digestive Enzymes for Digestion - Strengthens Gut

Pure Encapsulations Pancreatic Enzyme Formula - Digestive Enzymes for Digestion - Strengthens Gut
8.9

Pure Encapsulations

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  • Digestive Enzyme Blend for Gut Health: Contains amylase enzyme, lipase enzyme, and protease enzyme supplement to support natural digestion*
  • Targeted Delivery Capsules: Acid-resistant capsules ensure enzymes for digestionincluding our protease, amylase, and lipasereach the G.I. tract*
  • Concentrated Pancreatin: Each capsule provides 500 mg of pancreatin for digestive function support, strengthening gut health and aiding digestion*
  • Suggested Use: As a dietary supplement, take 1 digestive enzymes capsule, 3 times daily, with each meal, or as directed by a health professional
  • Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs

5. Pancreatin Digestive Enzymes Digestion for Gut Health - Pancreatic Digestive Enzymes for Women & Men

Pancreatin Digestive Enzymes Digestion for Gut Health - Pancreatic Digestive Enzymes for Women & Men
8.7

Natures Craft

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  • Pancreatin 4X - This proven combination of pure digestive enzymes for pancreas support and digestive health helps break down the main building blocks of food to keep your body functioning at its best
  • Simple but Effective Digestion Supplement - Pancreatic enzyme supplements work by supplementing the bodys natural enzyme supply to ensure nutrient absorption and digestion to help prevent blockages
  • 3 in 1 Formula - The amylase enzyme is to help digest carbs and minimize related bloating The lipase enzyme is for digesting fats and the protease enzyme supplement is for breaking down proteins
  • Trusted Brand - Forget about generic brands and put your trust in Natures Craft and our 3rd party lab tested digestive enzyme supplements made in GMP American facilities with non GMO ingredients
  • Natures Craft Quality - We are proud to be a leading name in a variety of potent digestion and digestive enzymes for men and women because we know just how important gut health can be for adults

6. NOW Supplements, Pancreatin 10X 200 mg with naturally occurring Protease (Protein Digesting),

NOW Supplements, Pancreatin 10X 200 mg with naturally occurring Protease (Protein Digesting),
8.5

Now Foods

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  • DIGESTIVE SUPPORT*: Pancreatin has naturally occurring protease (protein digesting), amylase (carbohydrate digesting), and lipase (fat digesting) enzymes
  • ASSISTS PROTEIN, FAT, AND CARBOHYDRATE DIGESTION*: Pancreatin is a preparation of porcine pancreatic enzymes
  • CERTIFICATIONS/CLASSIFICATIONS: Keto Friendly, Soy Free, Nut Free, Made without Gluten, Dairy Free, Egg Free
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
  • Packaged in the USA by a family owned and operated company since 1968

7. Carlyle Pancreatin Digestive Enzymes | 3000mg | 250 Caplets | Non-GMO, Gluten Free | High Potency

Carlyle Pancreatin Digestive Enzymes | 3000mg | 250 Caplets | Non-GMO, Gluten Free | High Potency
8.3

Carlyle

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  • PANCREATIC ENZYMES: Features Pancreatin, Amylase, Protease, and Lipase, for multi-enzyme support
  • ULTRA STRENGTH: Provides the equivalent of 3,000 mg of Pancreatin per serving in coated caplets
  • ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living
  • CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
  • NATURALLY FREE OF: Gluten, Wheat, Yeast, Lactose, Soy, Artificial Flavor, Preservatives & Non-GMO

8. Pure Encapsulations Pancreatic Enzyme Formula - Digestive Enzymes for Digestion - Strengthens Gut

Pure Encapsulations Pancreatic Enzyme Formula - Digestive Enzymes for Digestion - Strengthens Gut
8

Pure Encapsulations

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  • Digestive Enzyme Blend for Gut Health: Contains amylase enzyme, lipase enzyme, and protease enzyme supplement to support natural digestion*
  • Targeted Delivery Capsules: Acid-resistant capsules ensure enzymes for digestionincluding our protease, amylase, and lipasereach the G.I. tract*
  • Concentrated Pancreatin: Each capsule provides 500 mg of pancreatin for digestive function support, strengthening gut health and aiding digestion*
  • Suggested Use: As a dietary supplement, take 1 digestive enzymes capsule, 3 times daily, with each meal, or as directed by a health professional
  • Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs

9. Designs for Health Pancreatic Enzymes Complex - Digestive Enzymes + Bromelain Supplement - Support

Designs for Health Pancreatic Enzymes Complex - Digestive Enzymes + Bromelain Supplement - Support
7.9

Designs For Health

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  • Pancreatic Enzymes & Ox Bile - These pancreatic enzymes are nearly bioidentical to human enzymes and support protein, carbohydrate, and fat digestion. PaleoZyme also includes bromelain to promote protein digestion and ox bile to aid the emulsification of fats.*
  • Paleo Compliant - Free of grain, legume, and dairy-sourced ingredients, making it ideal for those with sensitivities to these common foods/food groups and those who prefer to maintain a strict Paleo diet.*
  • Delayed Release - Enteric coating protects the enzymes from stomach acid. This helps preserve their activity for the first section of small intestine, where pancreatic enzymes are intended to function.*
  • Higher Standards. Better Results - Designs for Health maintains a strict, no-compromises approach to quality raw material selection. We never cut corners with substandard ingredients. This product is Gluten-Free Non-GMO.
  • Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**

10. THORNE - Pancreatic Enzymes (Formerly Dipan-9) - Pancreatic Enzymes for Digestive Support and

  • Pancreatic Enzymes: Lipase, protease, and amylase support the digestion of fats, proteins, carbohydrates*
  • Absorption: Promotes the absorption of nutrients, especially fats*
  • Pancreatin: The highest purity and potency pancreatin available
  • Undiluted: Not diluted with lactose or any other excipients
  • Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

Peter

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