Best Gluten Digestive Enzymes

Peter | 04-01-2026

If you aren’t someone who makes frequent purchases, selecting the best Best Gluten Digestive Enzymes won’t be an easy chore for you. However, you shouldn’t be concerned because we have provided you with the most comprehensive list possible of the top Best Gluten Digestive Enzymes. Have a look at the products on our list, and pick the ones that appeal to you the most.

We researched and tested Best Gluten Digestive Enzymes in the market to get you this list. Our most recommended product is MaryRuth Organics Best Gluten Digestive Enzymes. Check out our picks for all of our favorites, and be sure to read our buying guide to get all the information you need to make the best choice!

Editor's Choice
Nature's Way Gluten Defense Digestive Enzymes*, Helps Digest Wheat & Dairy(1), Gluten & Casein
Nature's Way Gluten Defense Digestive Enzymes*, Helps Digest Wheat & Dairy(1), Gluten & Casein
Premium Pick
Enzymedica GlutenEase Extra Strength, Advanced Gluten Digestive Enzymes for Women and Men,
Enzymedica GlutenEase Extra Strength, Advanced Gluten Digestive Enzymes for Women and Men,
Budget Pick
365 by Whole Foods Market, Enzymes Gluten Digestive, 60 Count
365 by Whole Foods Market, Enzymes Gluten Digestive, 60 Count

Top 10 Best Gluten Digestive Enzymes

We researched and compared the top products in the Best Gluten Digestive Enzymes category to provide you with these recommendations.

1. MaryRuth’s Gluten Digestive Enzymes | Up to 2 Month Supply | Proprietary Enzyme Blend | Vegan

MaryRuth’s Gluten Digestive Enzymes | Up to 2 Month Supply | Proprietary Enzyme Blend | Vegan
8.7

Maryruth Organics

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  • Thoughtfully Formulated: These capsules feature a curated blend of enzymes in a simple and convenient capsule for those who enjoy incorporating enzyme-based supplements into their daily routine.
  • Proprietary Enzyme Blend: This formula features a unique blend of enzymes, biological substances known for catalyzing chemical reactions in the body.
  • Vegan & Pine-Based Capsules: These vegan pine-based capsules fit naturally into busy mornings, calm evenings, and everything in between with a portable capsule format.
  • Convenient & Travel-Friendly: Designed for everyday ease keep them at home or take them on the go to support a daily routine that feels natural to you.
  • For Most Lifestyles: MaryRuth's Gluten Enzymes are Non-GMO, Vegan, Dairy Free, Nut Free, Gluten Free, Soy Free, Sugar Free. Women Owned Business.

2. Nature's Way Gluten Defense Digestive Enzymes*, Helps Digest Wheat & Dairy(1), Gluten & Casein

Nature's Way Gluten Defense Digestive Enzymes*, Helps Digest Wheat & Dairy(1), Gluten & Casein
9.8

Nature's Way

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  • Nature's Way Gluten Defense provides enzymes for digestion for help with wheat and dairy*(1)
  • With gluten and casein digestive enzymes*
  • Adults take 2 gluten digestive enzyme capsules with each meal*
  • Vegan. No dairy, gelatin, or artificial colors or flavors
  • At Natures Way, we believe nature is the ultimate problem solver. For over 50 years, we have looked to the natural world for inspiration. Our quality vitamins and supplements are formulated to help you find your way to wellness

3. 365 by Whole Foods Market, Enzymes Gluten Digestive, 60 Count

365 by Whole Foods Market, Enzymes Gluten Digestive, 60 Count
9.1

365 By Whole Foods Market

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  • 60 gluten digestive enzyme capsules
  • Vegan formula targets gluten proteins
  • Supports digestion of foods containing gluten
  • Made with premium enzyme blend
  • Easy-to-swallow capsules

4. NOW Foods Supplements, Gluten Digest with BioCore®DPP IV, Gastrointestinal Support*, 60 Veg

NOW Foods Supplements, Gluten Digest with BioCore®DPP IV, Gastrointestinal Support*, 60 Veg
7.7

Now Foods

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  • GASTROINTESTINAL SUPPORT*/HELPS DIGEST GLUTEN AND CEREAL GRAINS: Take 1 capsule at the beginning of any meal that may contain gluten
  • SPECIALLY FORMULATED INGREDIENT: NOW Gluten Digest, with BioCore DPP IV, is a comprehensive enzyme blend formulated to promote the complete digestion of cereal grains*
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Kosher, Soy Free, Vegan/Vegetarian, Keto Friendly, Made without Gluten
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
  • Packaged in the USA by a family owned and operated company since 1968

5. Enzymedica GlutenEase, Advanced Digestive Enzymes for Women and Men, Fast-Acting Formula for

Enzymedica GlutenEase, Advanced Digestive Enzymes for Women and Men, Fast-Acting Formula for
8.7

Enzymedica

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  • DIGEST GLUTEN & CASEIN CONFIDENTLY GlutenEase includes targeted digestive enzymes to help break down gluten and casein, supporting comfortable digestion and occasional bloating relief for women and men sensitive to gluten.*
  • TARGETED GLUTEN ENZYME SUPPORT Features DPP-IV and Thera-blend protease enzymes to help digest gluten, casein, proteins, and carbs. Supports digestive health and occasional digestive discomfort after gluten-heavy meals.*
  • THERA-BLEND TECHNOLOGY Our exclusive Thera-blend protease enzyme formula works across all pH levels to support nutrient breakdown. A trusted gluten digestive enzyme for occasional gas relief in adults for those sensitive to gluten and casein.
  • SIMPLE & CLEAN FORMULA Just one capsule helps break down up to 19g protein and 56g carbs.* Free from gluten, casein, and soy,. Vegan and kosher.
  • ENZIMAS DIGESTIVAS AVANZADAS Enzymedica GlutenEase usa DPP-IV y Thera-blend para facilitar la digestin de gluten, casena y ms. Apoya la reduccin de hinchazn y gases ocasionales. Vegano, kosher y libre de colorantes, lcteos y gluten.*

6. Enzymedica GlutenEase Extra Strength, Advanced Gluten Digestive Enzymes for Women and Men,

Enzymedica GlutenEase Extra Strength, Advanced Gluten Digestive Enzymes for Women and Men,
9.5

Enzymedica

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  • EXTRA GLUTEN DIGESTION SUPPORT GlutenEase Extra Strength delivers more enzyme power compared to Enzymedica GlutenEase to help break down gluten and casein, supporting comfortable digestion and occasional gas relief for adults.*
  • ADVANCED ENZYME BLEND Enzymedica digestive enzymes with Thera-Blend stay active throughout the digestive tract to support nutrient breakdown and digestive comfort. Provides occasional bloating relief for women and men sensitive to gluten and casein.*
  • POWERFUL GLUTEN FORMULA Features DPP-IV and a unique Thera-Blend protease enzyme complex to help digest gluten, casein, and grains. Supports digestive health and helps reduce occasional bloating after meals.*
  • SIMPLE DAILY DOSAGE Just 1 capsule per meal helps digest up to 30g protein and 56g carbs.* Vegan, kosher, and clean-label formula free from gluten, dairy, soy, and artificial ingredients.*
  • ENZIMAS DIGESTIVAS AVANZADAS GlutenEase Extra Strength ayuda a descomponer gluten y casena con DPP-IV y Thera-Blend. Frmula vegana, kosher y sin gluten, lcteos, soja ni colorantes artificiales.*

7. Enzymedica GlutenEase, Advanced Digestive Enzymes for Women and Men, Fast-Acting Formula for

Enzymedica GlutenEase, Advanced Digestive Enzymes for Women and Men, Fast-Acting Formula for
8.3

Enzymedica

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  • DIGEST GLUTEN & CASEIN CONFIDENTLY GlutenEase includes targeted digestive enzymes to help break down gluten and casein, supporting comfortable digestion and occasional bloating relief for women and men sensitive to gluten.*
  • TARGETED GLUTEN ENZYME SUPPORT Features DPP-IV and Thera-blend protease enzymes to help digest gluten, casein, proteins, and carbs. Supports digestive health and occasional digestive discomfort after gluten-heavy meals.*
  • THERA-BLEND TECHNOLOGY Our exclusive Thera-blend protease enzyme formula works across all pH levels to support nutrient breakdown. A trusted gluten digestive enzyme for occasional gas relief in adults for those sensitive to gluten and casein.
  • SIMPLE & CLEAN FORMULA Just one capsule helps break down up to 19g protein and 56g carbs.* Free from gluten, casein, and soy,. Vegan and kosher.
  • ENZIMAS DIGESTIVAS AVANZADAS Enzymedica GlutenEase usa DPP-IV y Thera-blend para facilitar la digestin de gluten, casena y ms. Apoya la reduccin de hinchazn y gases ocasionales. Vegano, kosher y libre de colorantes, lcteos y gluten.*

8. Pure Encapsulations Gluten/Dairy Digest | Unique Mix of Enzymes to Support Healthy Gluten and Dairy

Pure Encapsulations Gluten/Dairy Digest | Unique Mix of Enzymes to Support Healthy Gluten and Dairy
9.1

Pure Encapsulations

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  • Digestion Support: Offers the unique Tolerase G prolyl-endopeptidase enzyme at the level designed to target the breakdown of 500 mg gluten. Tolerase G is not intended to replace a gluten-free.
  • Gastrointestinal Comfort Support: May support G.I. comfort and function.*
  • Gastrointestinal Health: Helps to relieve occasional bloating or gas due to dairy consumption.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn't just our process or what goes into our supplements -- what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

9. Enzymedica GlutenEase Extra Strength, Advanced Gluten Digestive Enzymes for Women and Men,

Enzymedica GlutenEase Extra Strength, Advanced Gluten Digestive Enzymes for Women and Men,
7.9

Enzymedica

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  • EXTRA GLUTEN DIGESTION SUPPORT GlutenEase Extra Strength delivers more enzyme power compared to Enzymedica GlutenEase to help break down gluten and casein, supporting comfortable digestion and occasional gas relief for adults.*
  • ADVANCED ENZYME BLEND Enzymedica digestive enzymes with Thera-Blend stay active throughout the digestive tract to support nutrient breakdown and digestive comfort. Provides occasional bloating relief for women and men sensitive to gluten and casein.*
  • POWERFUL GLUTEN FORMULA Features DPP-IV and a unique Thera-Blend protease enzyme complex to help digest gluten, casein, and grains. Supports digestive health and helps reduce occasional bloating after meals.*
  • SIMPLE DAILY DOSAGE Just 1 capsule per meal helps digest up to 30g protein and 56g carbs.* Vegan, kosher, and clean-label formula free from gluten, dairy, soy, and artificial ingredients.*
  • ENZIMAS DIGESTIVAS AVANZADAS GlutenEase Extra Strength ayuda a descomponer gluten y casena con DPP-IV y Thera-Blend. Frmula vegana, kosher y sin gluten, lcteos, soja ni colorantes artificiales.*

10. Healthy Digestives Gluten Cutter Enzyme Formula - Helps Improve Your Bodies Gluten Digestion and

Healthy Digestives Gluten Cutter Enzyme Formula - Helps Improve Your Bodies Gluten Digestion and
7.7

Healthy Delights

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  • Helps Digest Gluten Found in Wheat and Other Grains*
  • Helps Digest Lactose Found in Dairy Products*
  • Breaks Down Other Hard-to-Digest Foods*
  • Only Gluten Cutter Contains the GCX50 Gluten Blend

Peter

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