With so many Best Preservative Free Eye Drop brands on the market – from prominent names like Systane,Refresh,TheraTears to smaller manufacturers – making the right choice can feel overwhelming. But we’re here to help simplify your search for the best product.
We extensively tested and evaluated dozens of top-rated Best Preservative Free Eye Drop across various price points, spending over 100 hours comparing the contenders side-by-side. Based on our in-depth first-hand research, we compiled this list of stand-out Best Preservative Free Eye Drop to consider. Our top recommendation is Systane Best Preservative Free Eye Drop for its uncompromising quality and performance.
Below you’ll discover more of our favorite Best Preservative Free Eye Drop picks. And be sure to consult our buying guide for expert insights on selecting the ideal product for your individual needs and budget. With us guiding your decision, you can shop confidently knowing you’ve chosen an exceptional Best Preservative Free Eye Drop you’ll truly love.
Editor's Choice
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1)
Premium Pick
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count,
Budget Pick
TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30
Top 10 Best Preservative Free Eye Drop
We researched and compared the top products in the Best Preservative Free Eye Drop category to provide you with these recommendations.
1. Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1)
- Fast acting hydration for sensitive eyes
- Preservative free tear evaporation protection
- Nano droplets for better coverage
2. Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count,
- Original strength, preservative-free formula
- Relieves mild symptoms of eye dryness
- Instantly moisturizes and lubricates
- Designed to act like your own natural tears
- Great for sensitive eyes
- Value size. 50 on-the go, single-use vials
- Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
- The selling brand in preservative-free artificial tears. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
3. TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30
- TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms
- Discover TheraTears eye drops, one-of-a-kind silky hydration for dry eyes
- TheraTears Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
- TheraTears corrects the salt imbalance that can cause dry eye symptoms
- Preservative free for sensitive eyes; the single-use vials come in a foil pouch to ensure freshness
- Doctor recommended and created; TheraTears was created by an ophthalmologist after 18 years of research
- Contains 1 box of TheraTears Dry Eye Therapy Lubricant Drops, Preservative Free, 30 vials
- FSA- and HSA-eligible product in the U.S.
4. Systane Ultra Multi-Dose Preservative-Free Eye Drops Twin Pack (2x10ml)
- Preservative-Free Lubricant Eye Drops
- Fast-Acting Hydration and lasting dry eye relief
- Moisture rich formula eye drops for sensitive eyes
- Tear evaporation protection for high-performance dry eye symptom relief that lasts
5. Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
- Hydrates fast and provides long-lasting relief for dry eyes
- Preservative free eye drops
- Contains hyaluronate for advanced hydration
- Safe for use with all contact lenses
- Extra moisturizing eye drops for sensitive eyes
6. Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
- ORIGINAL STRENGTH: Provides temporary relief for mild, occasional dry eye symptoms
- FAST-ACTING: Instantly lubricates and moisturizes
- PRESERVATIVE-FREE: Great for sensitive eyes
- SOFT SQUEEZE MULTIDOSE BOTTLE: Features a double lockout system that keeps drops sterile
- TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
- FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan
7. Systane Ultra Lubricant Eye Drops, 60 Count (Pack of 1), (Packaging may vary)
- #1 Dr Recommended Brand of Artificial Tears*
- Extended Protection
- Fast Long-Lasting Dry Eye Symptom Relief
- Reduces both the signs and symptoms of dry eye
- Single-Use Convenience. Store at room temperature
8. iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief,
- Your Dry Eyes Deserve Better: iVIZIA Dry Eye drops are scientifically formulated to moisturize and lubricate dry eyes and relieve discomfort and eye strain due to dryness.
- Unique Formulation: Hydrating polymers form a protective matrix, moisturizing Hyaluronic Acid holds up to 1000x its weight in moisture, and Trehalose (synthetic ingredient also found in desert plants).
- Free of Irritating Preservatives: Sterile, safe for use with contact lenses
- Patented ABAK Bottle: preservative-free, dispenses drop-by-drop, and does not stream. The ergonomic bottle is easy to open, easy to hold and squeeze.
- iVIZIA We See a Better Way: for healthy, comfortable eyes
9. Refresh Plus Lubricant Eye Drops Preservative-Free Tears, 0.01 fl oz (0.4 mL), 70 Single-Use
- Original strength, preservative-free formula
- Relieves mild symptoms of eye dryness
- Instantly moisturizes and lubricates
- Designed to act like your own natural tears
- Great for sensitive eyes
- Value size. 70 on-the go, single-use vials
- Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
- The selling brand in preservative-free artificial tears. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
- Active Ingredient: Carboxymethylcellulose Sodium (CMC) (0.5%); Inactive Ingredients: Calcium Chloride, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Chloride, and Sodium Lactate. May also Contain Hydrochloric Acid and/or Sodium Hydroxide to Adjust pH.
10. TheraTears Extra Dry Eye Therapy Lubricant Eye Drops Preservative Free 30ct, 30 Count
- Get up to 12 Hours of Hydrating Comfort; TheraTears EXTRA Dry Eye Therapy Lubricant Eye Drops; Preservative Free; provide EXTRAordinary relief
- Discover TheraTears eye drops, one-of-a-kind silky hydration for dry eyes
- Lubricating eye drops for extra dry eyes rehydrate, protect against further irritation and support a natural tear pH level
- TheraTears Extra Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
- Preservative free for sensitive eyes; the single-use vials come in a foil pouch to ensure freshness
Peter
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